An efficient system to generate monoclonal antibodies against membrane-associated proteins by immunisation with antigen-expressing mammalian cells (Publications)
ABSTRACT: BACKGROUND: The generation of monoclonal antibodies specific for protein antigens usually depends on purified recombinant protein for both immunisation and hybridoma screening. Purification
A new rapid diagnostic test for detection of anti-<em>Schistosoma mansoni</em> and anti-<em>Schistosoma haematobium</em> antibodies (Publications)
ABSTRACT: BACKGROUND: Parasitological methods are widely used for the diagnosis of schistosomiasis. However, they are insensitive, particularly in areas of low endemicity, and labour-intensive. Immuno
Efficacy and safety of praziquantel in preschool-aged children in an area co-endemic for <em>Schistosoma mansoni</em> and <em>S. haematobium</em> (Publications)
BACKGROUND: In sub-Saharan Africa the recommended strategy to control schistosomiasis is preventive chemotherapy. Emphasis is placed on school-aged children, but in high endemicity areas, preschool-ag
Temporal correlation between malaria and rainfall in Sri Lanka (Publications)
BACKGROUND: Rainfall data have potential use for malaria prediction. However, the relationship between rainfall and the number of malaria cases is indirect and complex. METHODS: The statistical relati
Formation of the circumsporozoite protein of <em>Plasmodium falciparum</em> in <em>Anopheles stephensi</em> (Publications)
The place and time of synthesis of the circumsporozoite protein of P. falciparum was analysed with a monoclonal antibody directed against the (NANP)3 repetitive epitope of the CS protein. By using an
Socio-cultural determinants of adiposity and physical activity in preschool children: a cross-sectional study (Publications)
BACKGROUND: Both individual socio-cultural determinants such as selected parental characteristics (migrant background, low educational level and workload) as well as the regional environment are relat