An unusual type IB topoisomerase from African trypanosomes (Publications)
African trypanosomes are ancient eukaryotes that cause lethal disease in humans and cattle. Available drugs are inadequate and the need for new therapeutic targets is great. Trypanosoma brucei and rel
Topoisomerases in kinetoplastids (Publications)
Topoisomerases are enzymes that mediate topological changes in DNA that are essential for nucleic acid biosynthesis and for cell survival. The kinetoplastid protozoa, which include pathogenic trypanos
Work area measurements as predictors of personal exposure to endotoxin and cotton dust in the cotton textile industry (Publications)
OBJECTIVES: To determine if work area measurements of endotoxin and/or cotton dust obtained from the vertical elutriator (VE) can be used to predict levels of personal endotoxin exposure as measured b
Reduced lung cancer mortality and exposure to synthetic fluids and biocide in the auto manufacturing industry (Publications)
OBJECTIVES: Water-based soluble and synthetic metalworking fluids (MWF) used in auto manufacturing may be contaminated by endotoxin from Gram-negative bacteria, a possible anticarcinogen via increased
Airflow limitation and changes in pulmonary function among bleachery workers (Publications)
This study investigated whether chronic airflow limitation and rapid decline in pulmonary function were associated with peak exposures to ozone and other irritant gases in pulp mills. Bleachery worker
Exposure to ozone gases in pulp mills and the onset of rhinitis (Publications)
OBJECTIVE: Rhinitis is a common upper respiratory disease influenced by both genetic and environmental factors. It is also accepted that allergic rhinitis may precede asthma, a disease with more serio