Performance of HRP-2 based rapid diagnostic test for malaria and its variation with age in an area of intense malaria transmission in southern... (Publications)
BACKGROUND: The use of malaria rapid diagnostic tests (RDTs) has been widely advocated to improve Plasmodium falciparum diagnosis, especially in settings where quality microscopy is not available. RDT
Cell biological characterization of the malaria vaccine candidate trophozoite exported protein 1 (Publications)
In a genome-wide screen for alpha-helical coiled coil motifs aiming at structurally defined vaccine candidates we identified PFF0165c. This protein is exported in the trophozoite stage and was named a
Clonal waves of <em>Neisseria</em> colonisation and disease in the African meningitis belt: eight- year longitudinal study in Northern Ghana (Publications)
BACKGROUND: The Kassena-Nankana District of northern Ghana lies in the African "meningitis belt" where epidemics of meningococcal meningitis have been reoccurring every eight to 12 years for the last
Varying efficacy of intermittent preventive treatment for malaria in infants in two similar trials: public health implications (Publications)
BACKGROUND: Intermittent preventive treatment (IPTi) with sulphadoxine-pyrimethamine (SP) in infants resulted in different estimates of clinical malaria protection in two trials that used the same pro
Exposure to moderate air pollution during late pregnancy and cord blood cytokine secretion in healthy neonates (Publications)
BACKGROUND/OBJECTIVES: Ambient air pollution can alter cytokine concentrations as shown in vitro and following short-term exposure to high air pollution levels in vivo. Exposure to pollution during la
Optimization and validation of multi-coloured capillary electrophoresis for genotyping of <em>Plasmodium falciparum</em> merozoite surface proteins... (Publications)
BACKGROUND: Genotyping of Plasmodium falciparum based on PCR amplification of the polymorphic genes encoding the merozoite surface proteins 1 and 2 (msp1 and msp2) is well established in the field of