Artemisinin-based combination therapy does not measurably reduce human infectiousness to vectors in a setting of intense malaria transmission (Publications)
BACKGROUND: Artemisinin-based combination therapy (ACT) for treating malaria has activity against immature gametocytes. In theory, this property may complement the effect of terminating otherwise leng
SCYX-7158, an orally-active benzoxaborole for the treatment of stage 2 human African trypanosomiasis (Publications)
BACKGROUND: Human African trypanosomiasis (HAT) is an important public health problem in sub-Saharan Africa, affecting hundreds of thousands of individuals. An urgent need exists for the discovery and
Soil-transmitted helminth reinfection after drug treatment: a systematic review and meta-analysis (Publications)
BACKGROUND: Soil-transmitted helminth (STH) infections (i.e., Ascaris lumbricoides, hookworm, and Trichuris trichiura) affect more than a billion people. Preventive chemotherapy (i.e., repeated admini
Decreased availability of antimalarials in the private sector following the policy change from chloroquine to sulphadoxine-pyrimethamine in the... (Publications)
BACKGROUND: Malaria control strategies emphasize the need for prompt and effective treatment of malaria episodes. To increase treatment efficacy, Tanzania changed its first-line treatment from chloroq
Microbial larvicide application by a large-scale, community-based program reduces malaria infection prevalence in urban Dar es Salaam, Tanzania (Publications)
BACKGROUND: Malaria control in Africa is most tractable in urban settlements yet most research has focused on rural settings. Elimination of malaria transmission from urban areas may require larval co
From good intentions to proven interventions: effectiveness of actions to reduce the health impacts of air pollution (Publications)
Background: Associations between air pollution and a multitude of health effects are now well established. Given ubiquitous exposure to some level of air pollution, the attributable health burden can
