Maturation and mip-1beta production of cytomegalovirus-specific T cell responses in Tanzanian children, adolescents and adults: impact by HIV and... (Publications)
It is well accepted that aging and HIV infection are associated with quantitative and functional changes of CMV-specific T cell responses. We studied here the expression of Mip-1beta and the T cell ma
Association between advanced glycation end products and impaired fasting glucose: results from the SALIA study (Publications)
Advanced glycation end products (AGEs) may contribute to the development of type 2 diabetes and related complications, whereas their role in the early deterioration of glycaemia is unknown. While prev
Repurposing of anticancer drugs: <em>in vitro</em> and<em> in vivo</em> activities against <em>Schistosoma mansoni</em> (Publications)
BACKGROUND: Drug discovery for the neglected tropical disease schistosomiasis has a high priority. Anticancer drugs, especially protein kinase inhibitors, might serve as a starting point for drug disc
Locally confined clonal complexes of <em>Mycobacterium ulcerans</em> in two Buruli ulcer endemic regions of Cameroon (Publications)
BACKGROUND: Mycobacterium ulcerans is the causative agent of the necrotizing skin disease Buruli ulcer (BU), which has been reported from over 30 countries worldwide. The majority of notified patients
Targeting the parasite's DNA with methyltriazenyl purine analogs is a safe, selective and efficacious antitrypanosomal strategy (Publications)
The human and veterinary disease complex known as African trypanosomiasis continues to inflict significant global morbidity, mortality and economic hardship. Drug resistance and toxic side effects of
Malaria eradication and elimination: views on how to translate a vision into reality (Publications)
Although global efforts in the past decade have halved the number of deaths due to malaria, there are still an estimated 219 million cases of malaria a year, causing more than half a million deaths. I
An operational comparative study of quinine and artesunate for the treatment of severe malaria in hospitals and health centres in the Democratic... (Publications)
BACKGROUND: The Democratic Republic of the Congo (DRC) has the highest number of severe malaria cases in the world. In early 2012, the National Malaria Control Programme (NMCP) changed the policy for
