Cytotoxic and haemolytic steroidal glycosides from the Caribbean sponge <em>Pandaros acanthifolium</em> (Publications)
Six new steroidal saponins, pandarosides K-M (1-3) and their methyl esters (4-6), were isolated as minor components, after a careful chemical reinvestigation of the Caribbean sponge Pandaros acanthifo
Quantitative assessment of eosinophiluria in <em>Schistosoma haematobium</em> infections: a new marker of infection and bladder morbidity (Publications)
Eosinophiluria, as quantified by measuring eosinophil cationic protein (ECP) in urinary extracts, microhematuria, egg excretion, and ultrasound-detectable bladder pathology were recorded in Schistosom
The effect of the cyclin D1 (CCND1) A870G polymorphism on colorectal cancer risk is modified by glutathione-S-transferase polymorphisms and... (Publications)
Cyclin D1 (CCND1) regulates cellular decision between proliferation and growth arrest. Despite the functional relevance of the CCND1 A870G single nucleotide polymorphism (SNP) published results on its
One-hour rule-out and rule-in of acute myocardial infarction using high-sensitivity cardiac troponin T (Publications)
BACKGROUND High-sensitivity cardiac troponin (hs-cTn) assays seem to improve the early diagnosis of acute myocardial infarction (AMI), but it is unknown how to best use them in clinical practice. Our
Synthesis and antitrypanosomal evaluation of derivatives of N-benzyl-1,2-dihydroquinolin-6-ols: effect of core substitutions and salt formation (Publications)
Analogs of the trypanocidal lead compound 1-benzyl-1,2-dihydro-2,2,4-trimethylquinolin-6-yl acetate were prepared to extend the structure-activity relationship in this series of molecules, improve the
A Bayesian approach to estimate the age-specific prevalence of <em>Schistosoma mansoni</em> and implications for schistosomiasis control (Publications)
Models that accurately estimate the age-specific infection prevalence of Schistosoma mansoni can be useful for schistosomiasis control programmes, particularly with regard to whether mass drug adminis
Increased and expedited case detection by Xpert MTB/RIF assay in childhood tuberculosis: a prospective cohort study (Publications)
Background. Diagnosis and timely treatment of tuberculosis in children is hampered by the absence of fast and reliable tests, especially in the era of human immunodeficiency virus (HIV). The aim of th