Synthesis and in vitro and in vivo evaluation of antimalarial polyamines (Publications)
We recently reported that 1,14-diphenylacetamide derivatives of spermine exhibit potent nM in vitro growth inhibition properties of Plasmodium falciparum. In an effort to expand the structure-activity
Economics of brucellosis impact and control in low-income countries (Publications)
Most data and evidence on the economic burden of brucellosis and the benefits of its control are from high-income and middle-income countries. However, the burden of brucellosis is greatest in low-inc
Cold extremities and difficulties initiating sleep: evidence of co-morbidity from a random sample of a Swiss urban population (Publications)
Difficulties initiating sleep (DIS) can frequently occur in psychiatric disorders but also in the general population. The primary vasospastic syndrome is a functional disorder of vascular regulation i
Estimating malaria transmission through mathematical models (Publications)
Evaluating the effectiveness of malaria control interventions on the basis of their impact on transmission is increasingly important as countries move from malaria control to pre-elimination programs.
Pharmacokinetics, <em>Trypanosoma brucei gambiense</em> efficacy and time of drug action of DB829, a preclinical candidate for treatment of second... (Publications)
Human African trypanosomiasis (HAT, sleeping sickness), a neglected tropical disease endemic to sub-Saharan Africa, is caused by the parasites Trypanosoma brucei (T. b.) gambiense and T. b. rhodesiens
Sociocultural context of suicidal behaviour in the Sundarban region of India (Publications)
The role of mental illness in nonfatal deliberate self-harm (DSH) is controversial, especially in Asian countries. This prospective study examined the role of psychiatric disorders, underlying social