Dialkylaminoalkyl derivatives of bicyclic compounds with antiplasmodial activity (Publications)
Dialkylaminoalkyl derivatives of 2-azabicyclo[3.2.2]nonanes and of bicyclo[2.2.2]octanes were prepared and their activities determined in vitro against the multiresistant K(1) strain of Plasmodium fal
Contacts between poultry farms, their spatial dimension and their relevance for avian influenza preparedness (Publications)
Ongoing economic losses by and exposure of humans to highly pathogenic avian influenza (HPAI) in poultry flocks across Asia and parts of Africa and Europe motivate also outbreak-free countries such as
Synthesis, inhibition potency, binding mode, and antiprotozoal activities of fluorescent inhibitors of trypanothione reductase based on... (Publications)
Trypanothione reductase (TR) is a flavoenzyme unique to trypanosomatid parasites and a target for lead discovery programs. Various inhibitor scaffolds have emerged in the past, exhibiting moderate aff
Field evaluation of a recombinant glutathione S-transferase-based pyrethroid quantification assay (Publications)
A recombinant glutathione S-transferase (GST)-based pyrethroid quantification assay was field-tested in Ifakara, Tanzania. Initial laboratory tests suggested that all reagents used in the assay should
Pan-dengue virus detection by PCR for travelers returning from the tropics (Publications)
We performed dengue virus (DENV) serology and quantitative real-time pan-DENV reverse transcription-PCR (RT-PCR) on 186 sera of 171 patients returning from the tropics. DENV loads significantly decrea
Symptoms and transmission of intestinal cryptosporidiosis (Publications)
Cryptosporidium spp are a cause of diarrhoea in toddlers. Symptoms and routes of transmission were investigated in a prospective case-control study in the city and surroundings of Basel, Switzerland.