Trisubstituted pyrimidines as efficacious and fast-acting antimalarials (Publications)
In this paper we describe the optimization of a phenotypic hit against Plasmodium falciparum, based on a trisubstituted pyrimidine scaffold. This led to compounds with good pharmacokinetics and oral a
The internal migration between public and faith-based health providers: a cross-sectional, retrospective and multicentre study from southern Tanzania (Publications)
OBJECTIVE: To assess the magnitude, direction and underlying dynamics of internal health worker migration between public and faith-based health providers from a hospital perspective. METHODS: Two comp
Efficacy and safety of artemether-lumefantrine dispersible tablets compared with crushed commercial tablets in African infants and children with... (Publications)
BACKGROUND: Combination treatments, preferably containing an artemisinin derivative, are recommended to improve efficacy and prevent Plasmodium falciparum drug resistance. Our aim was to show non-infe
Bayesian first order auto-regressive latent variable models for multiple binary sequences (Publications)
Longitudinal clinical trials often collect long sequences of binary data monitoring a disease process over time. Our application is a medical study conducted in the US by the Veterans Administration C
HIV-related travel restrictions: trends and country characteristics (Publications)
INTRODUCTION: Increasingly, HIV-seropositive individuals cross international borders. HIV-related restrictions on entry, stay, and residence imposed by countries have important consequences for this m
