Anti-trypanosomal activity of helenalin and some structurally related sesquiterpene lactones (Publications)
The anti-trypanosomal activity of six sesquiterpene lactones (helenalin, mexicanin I, 11alpha,13-dihydrohelenalin acetate, chamissonolide, ivalin and isoalantolactone) against the African Trypanosoma
A point mutation in codon 76 of <em>pfcrt </em>of <em>P. falciparum </em>is positively selected for by chloroquine treatment in Tanzania (Publications)
This study was undertaken to validate the relevance of Chloroquine (CQ) resistance markers pfcrt(76) and pfmdr1(86) in an endemic area in Tanzania. After treatment with CQ, recrudescence was distingui
Systems parasitology: effects of <em>Fasciola hepatica</em> on the neurochemical profile in the rat brain (Publications)
We characterize the integrated response of a rat host to the liver fluke Fasciola hepatica using a combination of (1)H nuclear magnetic resonance spectroscopic profiles (liver, kidney, intestine, brai
Screening of antifungal azole drugs and agrochemicals with an adapted alamarBlue-based assay demonstrates antibacterial activity of Croconazole... (Publications)
An Alamar Blue-based growth inhibition assay has been adapted for the thermosensitive and slow growing pathogen Mycobacterium ulcerans (M. ulcerans). The standardized test procedure enables medium-thr
Bacterial and fungal agents in house dust and wheeze in children: the PARSIFAL study (Publications)
BACKGROUND: Growing up on a farm and an anthroposophic lifestyle are associated with a lower prevalence of allergic diseases in childhood. This might be related to increased inhalatory exposure to mic
Species variation in the fecal metabolome gives insight into differential gastrointestinal function (Publications)
The metabolic composition of fecal extracts provides a window for elucidating the complex metabolic interplay between mammals and their intestinal ecosystems, and these metabolite profiles can yield i
Utilizing environmental, socioeconomic data and GIS techniques to estimate the risk for ascariasis and trichuriasis in Minas Gerais, Brazil (Publications)
The impact of intestinal helminths on human health is well known among the population and health authorities because of their wide geographic distribution and the serious problems they cause. Geohelmi
Sleepless night, the moon is bright: longitudinal study of lunar phase and sleep (Publications)
Popular belief holds that the lunar cycle affects human physiology, behaviour and health. We examined the influence of moon phase on sleep duration in a secondary analysis of a feasibility study of mo
Single pollutant versus surrogate measure approaches: do single pollutant risk assessments underestimate the impact of air pollution on lung cancer... (Publications)
Cancer risk as a result of air pollution may be quantified by different approaches. We compared the sum of unit risk based effects of single pollutants with an epidemiology-based method by using PM(10
