Pharmacometric analysis of tribendimidine mono- and combination therapies to achieve high cure rates in patients with hookworm infections (Publications)
To treat hookworm infections, pharmacotherapy has been only moderately successful and drug resistance is a threat. Therefore, novel treatment options including combination therapies should be consider
Population pharmacokinetics and exposure-response analysis of tribendimidine to improve treatment for children with hookworm infection (Publications)
Tribendimidine has been successful in treating hookworm infections and may serve as alternative to albendazole should resistance arise. Our aims were to (i) characterize the pharmacokinetics (PK) of t
Latent tuberculosis infection prevalence in rural Madagascar (Publications)
BACKGROUND: Understanding latent Mycobacterium tuberculosis infection (LTBI) prevalence is crucial for the design of TB control strategies. There are no data on LTBI in rural Madagascar. METHODS: Tube
The catalytic subunit of <em>Plasmodium falciparum</em> casein kinase 2 is essential for gametocytogenesis (Publications)
Casein kinase 2 (CK2) is a pleiotropic kinase phosphorylating substrates in different cellular compartments in eukaryotes. In the malaria parasite Plasmodium falciparum, PfCK2 is vital for asexual pro
Health seeking behavior among adults and elderly with chronic health condition(s) in Albania (Publications)
Aim: Assess the use of different health care service providers by adults (aged 18–59) and elderly (aged > =60) who suffer from non-communicable disease (NCD) and explore relationships between sociodem
Prevalence of vitamin D deficiency in an inpatient population in the Swiss canton of Basel-Country (Publications)
AIMS: Vitamin D deficiency remains very common in the general population. Adding to the importance of this issue is the discovery that vitamin D plays a role in many other tissues apart from the bone,
Genomic epidemiological analysis identifies high relapse among individuals with recurring tuberculosis and provides evidence of household recent TB... (Publications)
OBJECTIVE: We investigated the cause of recurring tuberculosis (rcTB) among pulmonary TB participants recruited from a prospective population-based study conducted between July 2012 and December 2015.
Outdoor air pollution and hormone-assessed pubertal development in children: results from the GINIplus and LISA birth cohorts (Publications)
BACKGROUND: Air pollution is hypothesized to affect pubertal development. However, the few studies on this topic yielded overall mixed results. These studies did not consider important pollutants like
Local adaptation in populations of <em>Mycobacterium tuberculosis</em> endemic to the Indian Ocean Rim (Publications)
Background: Lineage 1 (L1) and 3 (L3) are two lineages of the Mycobacterium tuberculosis complex (MTBC) causing tuberculosis (TB) in humans. L1 and L3 are prevalent around the rim of the Indian Ocean,
