Switch to second-line versus continued first-line antiretroviral therapy for patients with low-level HIV-1 viremia: an open-label randomized... (Publications)
BACKGROUND: Current World Health Organization (WHO) antiretroviral therapy (ART) guidelines define virologic failure as two consecutive viral load (VL) measurements > /=1,000 copies/mL, triggering emp
Costing malaria interventions from pilots to elimination programmes (Publications)
Background:Malaria programmes in countries with low transmission levels require evidence to optimize deploy-ment of current and new tools to reach elimination with limited resources. Recent pilots of
An in-depth report of quality control on Kato-Katz and data entry in four clinical trials evaluating the efficacy of albendazole against... (Publications)
BACKGROUND: Efforts to control soil-transmitted helminth (STH) infections have intensified over the past decade. Field-survey data on STH prevalence, infection intensity and drug efficacy is necessary
The roles of water, sanitation and hygiene in reducing schistosomiasis: a review (Publications)
Schistosomiasis is a disease caused by infection with blood flukes of the genus Schistosoma. Transmission of, and exposure to, the parasite result from faecal or urinary contamination of freshwater co
Resisting infection by <em>Plasmodium berghei</em> increases the sensitivity of the malaria vector <em>Anopheles gambiae</em> to DDT (Publications)
BACKGROUND: The evolution of insecticide resistance threatens current malaria control methods, which rely heavily on chemical insecticides. The magnitude of the threat will be determined by the phenot
Malaria risk in Nigeria: Bayesian geostatistical modelling of 2010 malaria indicator survey data (Publications)
BACKGROUND: In 2010, the National Malaria Control Programme with the support of Roll Back Malaria partners implemented a nationally representative Malaria Indicator Survey (MIS), which assembled malar
Distribution and risk factors for <em>Plasmodium</em> and helminth co-infections: a cross-sectional survey among children in Bagamoyo district,... (Publications)
BACKGROUND: Plasmodium and soil transmitted helminth infections (STH) are a major public health problem, particularly among children. There are conflicting findings on potential association between th