Structural requirements for dihydrobenzoxazepinone anthelmintics: actions against medically important and model parasites: <em>Trichuris muris</em>,... (Publications)
Nine hundred million people are infected with the soil-transmitted helminths Ascaris lumbricoides (roundworm), hookworm, and Trichuris trichiura (whipworm). However, low single-dose cure rates of the
Pathogens that cause acute febrile illness among children and adolescents in Burkina Faso, Madagascar and Sudan (Publications)
BACKGROUND: The etiology and optimal clinical management of acute febrile illness (AFI) is poorly understood. METHODS: Blood samples taken from study participants with acute fever (> /=37.5 degrees C)
Quality control of long-lasting insecticidal nets: are we neglecting it? (Publications)
Over 2.2 billion long-lasting insecticidal nets (LLINs) for malaria control have been delivered to recipient countries. LLINs are the largest single item in the global malaria control budget. To be el
Dynamics of intestinal multidrug-resistant bacteria colonisation contracted by visitors to a high-endemic setting: a prospective, daily, real-time... (Publications)
Background: Antimicrobial resistance is highly prevalent in low-income and middle-income countries. International travel contributes substantially to the global spread of intestinal multidrug-resistan
Efficacy and safety of ascending doses of moxidectin against<em> Strongyloides stercoralis</em> infections in adults: a randomised, parallel-group,... (Publications)
BACKGROUND: Strongyloidiasis represents a major public health issue, particularly in resource-limited countries. Preliminary studies suggest that moxidectin might serve as an alternative to the only a
Evaluation of a duplex real-time PCR in human serum for simultaneous detection and differentiation of <em>Schistosoma mansoni</em> and <em>Schistosoma... (Publications)
BACKGROUND: We evaluated a one-tube multiplex real-time PCR targeting DNA of Schistosoma haematobium complex and S. mansoni complex in serum samples obtained at different German diagnostic centers. ME
Neue Parameter für die Wirkstofftestung gegen <em>Trypanosoma cruzi</em> (Publications)
Chagas disease is a zoonosis caused by Trypanosoma cruzi and transmitted by triatomine bugs. Autochthonous to Latin America, Chagas disease has spread globally through travel and migration. New drugs
Short-term effects of nocturnal transportation noise on cardio-metabolic outcomes and its association to sleep (Publications)
Transportation noise is one of the most important environmental risk factors for cardio-metabolic diseases. It is assumed that short-term noise exposure activates a physiological stress response, whic
Mode of action of synthetic antimalarial peroxides (Publications)
Malaria is one of the most widespread infectious diseases which caused an estimated 212 million cases and 429,000 deaths worldwide in 2015. Today, artemisinin-based combination therapy (ACT), a combin
