Rapid mapping of schistosomiasis and other neglected tropical diseases in the context of integrated control programmes in Africa (Publications)
There is growing interest and commitment to the control of schistosomiasis and other so-called neglected tropical diseases (NTDs). Resources for control are inevitably limited, necessitating assessmen
Discrepancy in plasma melarsoprol concentrations between HPLC and bioassay methods in patients with <em>T. gambiense</em> sleeping sickness indicates... (Publications)
OBJECTIVE: With the use of a specific high-performance liquid chromatography (HPLC) method and a bioassay which determines trypanocidal activity, concentrations of melarsoprol were assessed in plasma,
Prevalence of airflow obstruction in smokers and never smokers in Switzerland (Publications)
We aimed to measure age-specific prevalence of airflow obstruction (AO) in Switzerland in smokers and never smokers using pulmonary function tests and respiratory symptoms from 6126 subjects participa
Alternative application of melarsoprol for treatment of <em>T.b. gambiense</em> sleeping sickness: preliminary results (Publications)
The protocols for treatment of human African trypanosomiasis (sleeping sickness) with the organoarsenical drug melarsoprol are based on empirical observations. Therapy is often accompanied by serious
Long-term decline in lung function, utilisation of care and quality of life in modified GOLD stage 1 COPD (Publications)
BACKGROUND: Little is known about the long-term outcomes of individuals with mild chronic obstructive pulmonary disease (COPD) as defined by the Global Initiative for Chronic Obstructive Lung Disease
Synthesis, structure-activity relationship, and mode-of-action studies of antimalarial reversed chloroquine compounds (Publications)
We have previously shown that a "reversed chloroquine (RCQ)" molecule, composed of a chloroquine-like moiety and a resistance reversal-like moiety, can overcome chloroquine resistance in P. falciparum
Shoot growth of mature Fagus sylvatica and Picea abies in relation to ozone (Publications)
Epidemiological analysis of sequential growth data may be a tool in assessing ozone sensitivity of mature trees. Annual shoot growth of mature Fagus sylvatica in 83 Swiss permanent forest observation