New derivatives of 4-aminobicyclo[2.2.2]octanones and -ols as potential antiprotozoals (Publications)
New derivatives of 4-aminobicyclo[2.2.2]octanones and -ols were prepared. Their structures were established by means of NMR experiments. All new compounds were tested for their activities against Plas
Synthesis and evaluation of the antitrypanosomal and antiplasmodial activities of new 4-aminobicyclo[2.2.2]octane derivatives (Publications)
Several new 4-amino-6,7-diphenylbicyclo[2.2.2]octane derivatives, methylthiosemicarbazones of bicyclo[2.2.2]octan-2-ones and esters of bicyclo[2.2.2]octan-2-ols were prepared. Their antitrypanosomal a
Isomerization of 4-amino-6,7-diphenylbicyclo[2.2.2]octan-2-ones (Publications)
Under strongly basic conditions (6SR,7SR)-4-amino-6,7-diphenylbicyclo[2.2.2]octan-2-ones isomerized regioselectively in position 6 giving their (6RS,7SR) analogues. The structure of the new products w
New 4-amino-2-azabicyclo[3.2.2]nonane derivatives and their antiprotozoal potencies (Publications)
Several 2-substituted 4-amino-2-azabicyclo [3.2.2]nonane derivatives were synthesized. The new compounds were investigated for their activities against the causative organism of East African sleeping
Field efficacy of thermally expelled or live potted repellent plants against African malaria vectors in western Kenya (Publications)
OBJECTIVE: To estimate the effectiveness of live potted plants and thermal expulsion of plant materials in repelling African malaria vectors in traditional houses in western Kenya. METHODS: Ocimum ame
Antiprotozoal polyacetylenes from the Tanzanian medicinal plant <em>Cussonia zimmermannii</em> (Publications)
From the petroleum ether extract of the root bark of Cussonia zimmermannii four polyacetylenes, 1- 4, were isolated, three of which ( 1- 3) were active against Trypanosoma brucei rhodesiense, Trypanos
