Benzo[b]quinolizinium derivatives have a strong antimalarial activity and inhibit indoleamine dioxygenase (Publications)
The heme-containing enzymes indoleamine 2,3-dioxygenase-1 and -2 (IDO-1, -2) catalyze the conversion of the essential amino acid tryptophan into kynurenine. Metabolites of the kynurenine pathway and I
Prevalence of malaria across Papua New Guinea after initial roll-out of insecticide-treated mosquito nets (Publications)
OBJECTIVES: To assess the population prevalence of malaria in villages across Papua New Guinea (PNG) following the first roll-out of free long-lasting insecticidal nets (LLIN). METHODS: Between Octobe
Exposing concerns about vaccination in low- and middle-income countries: a systematic review (Publications)
OBJECTIVES: Concerns about vaccination lead to under- and no-vaccination. Our objective is to synthesise and expose evidence on individuals' and communities' concerns about vaccination to influence cu
Mobile health applications for HIV prevention and care in Africa (Publications)
PURPOSE OF REVIEW: More people have mobile phones in Africa than at any point in history. Mobile health (m-health), the use of mobile phones to support the delivery of health services, has expanded in
Integrated health messaging for multiple neglected zoonoses: approaches, challenges and opportunities in Morocco (Publications)
Integrating the control of multiple neglected zoonoses at the community-level holds great potential, but critical data is missing to inform the design and implementation of different interventions. In
The extended AT-hook is a novel RNA binding motif (Publications)
The AT-hook has been defined as a DNA binding peptide motif that contains a glycine-arginine-proline (G-R-P) tripeptide core flanked by basic amino acids. Recent reports documented variations in the s
Global, regional, and national disability-adjusted life years (DALYs) for 306 diseases and injuries and healthy life expectancy (HALE) for 188... (Publications)
BACKGROUND: The Global Burden of Disease Study 2013 (GBD 2013) aims to bring together all available epidemiological data using a coherent measurement framework, standardised estimation methods, and tr
Problematic mobile phone use of Swiss adolescents: is it linked with mental health or behaviour? (Publications)
OBJECTIVES: To investigate the associations between problematic mobile phone use and mental health and behavioural problems in 412 Swiss adolescents owning a mobile phone while controlling for amount
Profile: the rusinga health and demographic surveillance system, western Kenya (Publications)
The health and demographic surveillance system on Rusinga Island, Western Kenya, was initiated in 2012 to facilitate a malaria intervention trial: the SolarMal project. The project aims to eliminate m
Potential for reduction of burden and local elimination of malaria by reducing <em>Plasmodium falciparum</em> malaria transmission: a mathematical... (Publications)
BACKGROUND: Rapid declines in malaria prevalence, cases, and deaths have been achieved globally during the past 15 years because of improved access to first-line treatment and vector control. We aimed
