Anti-protozoal and plasmodial FabI enzyme inhibiting metabolites of <em>Scrophularia lepidota</em> roots (Publications)
The ethanolic root extract of Scrophularia lepidota, an endemic plant of the Turkish flora, has been investigated for its anti-protozoal and inhibitory effect towards plasmodial enoyl-ACP reductase (F
Efficacy of the diamidine DB75 and its prodrug DB289, against murine models of human African trypanosomiasis (Publications)
The choice of drugs for the treatment of sleeping sickness is extremely limited. To redress this situation, the recently synthesised diamidine, 2,5-bis(4-amidinophenyl)-furan (DB75, furamidine) and it
Integrated cytokine and metabolic analysis of pathological responses to parasite exposure in rodents (Publications)
Parasitic infections cause a myriad of responses in their mammalian hosts, on immune as well as on metabolic level. A multiplex panel of cytokines and metabolites derived from four parasite-rodent mod
Immune deficiency in mouse models for inherited peripheral neuropathies leads to improved myelin maintenance (Publications)
The adhesive cell surface molecule P(0) is the most abundant glycoprotein in peripheral nerve myelin and fulfills pivotal functions during myelin formation and maintenance. Mutations in the correspond