Fluorescence/luminescence-based markers for the assessment of <em>Schistosoma mansoni</em> schistosomula drug assays (Publications)
BACKGROUND: Schistosomiasis is responsible for a tremendous public health burden, yet only a single drug, praziquantel, is available. New antischistosomal treatments should therefore be developed. The
DNA methylation assessed by SMRT sequencing is linked to mutations in <em>Neisseria meningitidis</em> isolates (Publications)
The Gram-negative bacterium Neisseria meningitidis features extensive genetic variability. To present, proposed virulence genotypes are also detected in isolates from asymptomatic carriers, indicating
Design and preparation of sterol mimetics as potential antiparasitics (Publications)
We have previously shown that azasterols have activity against Trypanosoma brucei, Trypanosoma cruzi and Leishmania species, which are the causative agents of various neglected tropical diseases. In t
Estimating phosphate removal in haemodialysis: an additional tool to quantify dialysis dose (Publications)
BACKGROUND: Half of the dialysis population suffers from hyperphosphataemia, which is now recognized as a major factor of haemodialysis (HD) morbidity and mortality. Current control is focussed on red
Long-term effects of ambient air pollution on lung function: a review (Publications)
Lung function is an important measure of respiratory health and a predictor of cardiorespiratory morbidity and mortality. Over the past 2 decades, more than 50 publications have investigated long-term
Malaria: burden of disease (Publications)
Despite more than 100 years since Laveran described plasmodium species and Ross confirmed that they were transmitted by female anopheline mosquitoes, malaria remains a leading cause of morbidity and m
