Efficacy and safety of a single-dose mebendazole 500 mg chewable, rapidly-disintegrating tablet for <em>Ascaris lumbricoides</em> and <em>Trichuris... (Publications)
This randomized, double-blind, placebo-controlled study evaluated the efficacy and safety of a new chewable, rapidly-disintegrating mebendazole (MBZ) 500 mg tablet for Ascaris lumbricoides and Trichur
State of inequality in malaria intervention coverage in sub-Saharan African countries (Publications)
BACKGROUND: Scale-up of malaria interventions over the last decade have yielded a significant reduction in malaria transmission and disease burden in sub-Saharan Africa. We estimated economic gradient
Indole and benzimidazole bichalcophenes: synthesis, DNA binding and antiparasitic activity (Publications)
A novel series of indole and benzimidazole bichalcophene diamidine derivatives were prepared to study their antimicrobial activity against the tropical parasites causing African sleeping sickness and
A novel electronic algorithm using host biomarker point-of-care tests for the management of febrile illnesses in Tanzanian children (e-POCT): a... (Publications)
BACKGROUND: The management of childhood infections remains inadequate in resource-limited countries, resulting in high mortality and irrational use of antimicrobials. Current disease management tools,
Barriers to access improved water and sanitation in poor peri-urban settlements of Abidjan, Côte d'Ivoire (Publications)
Achieving access to safe water and sanitation still pose major challenges in urban areas of sub-Saharan Africa countries, despite all the progress achieved in the last decade. This study assessed the
Precursor-directed diversification of cyclic tetrapeptidic pseudoxylallemycins (Publications)
Cyclic peptides containing non-proteinogenic amino acids often exhibit a broad bioactivity spectrum and many have entered clinical trials with good prospects for drug development. We recently reported
Boosting effect of IL-7 in interferon gamma release assays to diagnose <em>Mycobacterium tuberculosis</em> infection (Publications)
BACKGROUND: A quarter of the world's population is estimated to be infected with Myobacterium tuberculosis (Mtb). Infection is detected by immune response to M. tuberculosis antigens using either tube
