Dioncophyllines C2, D2, and F and related naphthylisoquinoline alkaloids from the Congolese liana <em>Ancistrocladus ileboensis</em> with potent... (Publications)
Dioncophylline F (1), the first 5,8'-coupled dioncophyllaceous alkaloid (i.e., lacking an oxygen function at C-6 and possessing an R-configuration at C-3), was isolated from the recently described Con
Cyclombandakamines A1 and A2, oxygen-bridged naphthylisoquinoline dimers from a Congolese <em>Ancistrocladus liana</em> (Publications)
Cyclombandakamines A1 (1) and A2 (2), both with an unprecedented pyrane-cyclohexenone-dihydrofuran sequence and six stereocenters and two chiral axes, are the first oxygen-bridged dimeric naphthylisoq
Structure of the malaria vaccine candidate antigen CyRPA and its complex with a parasite invasion inhibitory antibody (Publications)
Invasion of erythrocytes by Plasmodial merozoites is a composite process involving the interplay of several proteins. Among them, the Plasmodium falciparum Cysteine-Rich Protective Antigen (PfCyRPA) i
The extractive industry in Latin America and the Caribbean: health impact assessment as an opportunity for the health authority (Publications)
OBJECTIVES: The extractive industries have contributed to the economic and social development of Latin America and the Caribbean for centuries. We have undertaken a narrative review to assess the role
<em>Ascaris lumbricoides</em> egg die-off in an experimental excreta storage system and public health implication in Vietnam (Publications)
OBJECTIVES: We studied the influence of different additive materials (lime, and rice husk) and aeration conditions on Ascaris lumbricoides egg die-off in 24 vaults of an experimental excreta storage u
Antimalarial Pyrido[1,2-a]benzimidazoles (Publications)
A novel class of antimalarial pyrido[1,2-a]benzimidazoles were synthesized and evaluated for antiplasmodial activity and cytotoxicity following hits identified from screening commercially available co
