Development and validation of a clinical decision rule for the diagnosis of influenza (Publications)
INTRODUCTION: A clinical decision rule to improve the accuracy of a diagnosis of influenza could help clinicians avoid unnecessary use of diagnostic tests and treatments. Our objective was to develop
Prenatal exposure to a farm environment modifies atopic sensitization at birth (Publications)
BACKGROUND: Previous cross-sectional surveys have suggested that maternal exposure to animal sheds during pregnancy exerted a protective effect on atopic sensitization in children lasting until school
Okundoperoxide, a bicyclic cyclofarnesylsesquiterpene endoperoxide from <em>Scleria striatinux</em> with antiplasmodial activity (Publications)
Okundoperoxide (1) was isolated by bioassay-guided fractionation of extracts from Scleria striatinux (syn. S. striatonux). The compound contains a cyclic endoperoxide structural moiety and possesses m
Evaluation of the pharmacokinetic profile of artesunate, artemether and their metabolites in sheep naturally infected with <em>Fasciola hepatica</em> (Publications)
The pharmacokinetic (PK) parameters of artesunate, artemether and their metabolites dihydroartemisinin (DHA) and dihydroartemisinin-glucuronide (DHA-glucuronide) were determined in sheep naturally inf
<em>Fasciola hepatica</em>: comparison of the sedimentation and FLOTAC techniques for the detection and quantification of faecal egg counts in rats (Publications)
We compared the sedimentation and FLOTAC techniques for the detection and quantification of Fasciola hepatica eggs in faecal samples obtained from 120 experimentally-infected rats before intervention,
Abietane diterpenoids from <em>Salvia sahendica</em> - antiprotozoal activity and determination of their absolute configurations (Publications)
In a screening of Iranian plants for antiprotozoal activity, an n-hexane extract of the roots of Salvia sahendica potently inhibited the growth of Plasmodium falciparum K1 strain. Subsequent HPLC-base
Participatory mapping of target areas to enable operational larval source management to suppress malaria vector mosquitoes in Dar es Salaam, Tanzania (Publications)
ABSTRACT: BACKGROUND: Half of the population of Africa will soon live in towns and cities where it can be protected from malaria by controlling aquatic stages of mosquitoes. Rigorous but affordable an