Safety and tolerance of lymph node biopsies from chronic HIV-1 volunteers in rural Tanzania (Publications)
OBJECTIVE: HIV-1 rapidly establishes a persistent infection that can be contained under life-long antiretroviral therapy (ART) but not cured. One major viral reservoir is the peripheral lymph node (LN
Genome-wide mutational biases fuel transcriptional diversity in the <em>Mycobacterium tuberculosis</em> complex (Publications)
The Mycobacterium tuberculosis complex (MTBC) members display different host-specificities and virulence phenotypes. Here, we have performed a comprehensive RNAseq and methylome analysis of the main c
Host cytoskeleton remodeling throughout the blood stages of <em>Plasmodium falciparum</em> (Publications)
SUMMARYThe asexual intraerythrocytic development of Plasmodium falciparum, causing the most severe form of human malaria, is marked by extensive host cell remodeling. Throughout the processes of invas
Performance of prediction rules and guidelines in detecting serious bacterial infections among Tanzanian febrile children (Publications)
BACKGROUND: Health-workers in developing countries rely on clinical algorithms, such as the Integrated Management of Childhood Illnesses (IMCI), for the management of patients, including diagnosis of
Can trials of spatial repellents be used to estimate mosquito movement? (Publications)
BACKGROUND: Knowledge of mosquito movement would aid the design of effective intervention strategies against malaria. However, data on mosquito movement through mark-recapture or genetics studies are
Prospective European-wide multicentre study on a blood based real-time PCR for the diagnosis of acute schistosomiasis (Publications)
BACKGROUND: Acute schistosomiasis constitutes a rare but serious condition in individuals experiencing their first prepatent Schistosoma infection. To circumvent costly and time-consuming diagnostics,
