Mental health of individuals at increased suicide risk after hospital discharge and initial findings on the usefulness of a suicide prevention project... (Publications)
BACKGROUND: Supporting individuals in managing their suicidality can prevent suicidal behavior. This study evaluated the suicide prevention project SERO, which was launched in Central Switzerland in 2
Targeting <em>Plasmodium falciparum</em> IspD in the methyl-d-erythritol phosphate pathway: urea-based compounds with nanomolar potency on target and... (Publications)
The methyl-d-erythritol phosphate (MEP) pathway has emerged as an interesting target in the fight against antimicrobial resistance. The pathway is essential in many human pathogens, including Plasmodi
Vulnerability to heat-related mortality and the effect of prevention measures: a time-stratified case-crossover study in Switzerland (Publications)
BACKGROUND: Swiss climate scenarios predict increases in the frequency and intensity of extreme heat episodes in the future. For the effective prevention of heat-related mortality, several aspects of
A genome-focused investigation reveals the emergence of a <em>Mycobacterium tuberculosis</em> strain related to multidrug-resistant tuberculosis in... (Publications)
A previous study in Pará, Northern Brazil, described a strain of Mycobacterium tuberculosis with a unique genotype (SIT2517/T1) associated with multidrug-resistant tuberculosis (MDR-TB). To improve ou
Changes in seasonality and sex ratio of scrub typhus: a case study of South Korea from 2003 to 2019 based on wavelet transform analysis (Publications)
BACKGROUND: Scrub typhus (ST, also known as tsutsugamushi disease) is a common febrile vector-borne disease in South Korea and commonly known as autumn- and female-dominant disease. Although understan
From fragmentation to open access: building an open data portal for health data dissemination (Publications)
Open data is defined as data that can be used and redistributed by anyone with minimal or no restrictions. A design science research methodology was applied to the development of an open data portal f
Total synthesis of tosyl-samroiyotmycin A and its biological profiling (Publications)
A total synthesis of the enantiopure syn,syn-tosyl-samroiyotmycin A, a C2-symmetric 20-membered antimalarial macrodiolide with syn,syn-configuration of the 8,24-dihydroxy-9,25-dimethyl units and it's
Medium-ring keto bislactams with antischistosomal activity (Publications)
We discovered medium-ring keto bislactams as a new antischistosomal chemotype. The ketone functional group and isoindolinone substructure were required for high antischistosomal activity. Aryl substit
Rapid increase in the risk of heat-related mortality (Publications)
Heat-related mortality has been identified as one of the key climate extremes posing a risk to human health. Current research focuses largely on how heat mortality increases with mean global temperatu
