Safety and protective efficacy of PfSPZ vaccine administered to HIV negative and positive Tanzanian adults (Publications)
BACKGROUND: Sanaria PfSPZ Vaccine, composed of attenuated Plasmodium falciparum (Pf) sporozoites (SPZ), protects against malaria. We conducted this clinical trial to assess the safety and efficacy of
Testing the feasibility, acceptability, and exploring trends on efficacy of the problem management plus for moms: protocol of a pilot randomized... (Publications)
Mental health disorders are one of the most common causes that limit the ability of mothers to care for themselves and for their children. Recent data suggest high rates of distress among women in cha
Randomised controlled trial on the effect of social support on disease control, mental health and health-related quality of life in people with... (Publications)
INTRODUCTION: Diabetes mellitus (DM) and its severe complications contribute significantly to disability and, hence, burden of disease. Poor mental health, a frequent DM consequence, may hinder succes
Combining theory-driven realist approach and systems thinking to unpack complexity of type 2 diabetes and hypertension management in low and... (Publications)
The burden of type 2 diabetes mellitus (T2DM) and hypertension (HTN) has increased worldwide in recent decades, particularly in low- and middle-income countries (LMICs). In these countries, health sys
Induced pluripotent stem cell-derived human macrophages as an infection model for <em>Leishmania donovani</em> (Publications)
The parasite Leishmania donovani is one of the species causing visceral leishmaniasis in humans, a deadly infection claiming up to 40,000 lives each year. The current drugs for leishmaniasis treatment
Human African trypanosomiasis (Publications)
Human African trypanosomiasis (HAT) is a parasitic disease caused by Trypanosoma brucei gambiense or T.b. rhodesiense, transmitted by tsetse flies (Glossina spp.). HAT has a prominent history as it re
Tropical rickettsial infections (Publications)
Tropical rickettsial illnesses are severely neglected infectious diseases with a worldwide distribution. These diseases are transmitted by various vectors (mites, ticks, fleas, etc.) and are responsib
<em>Mycobacterium ulcerans</em> disease (Buruli ulcer) (Publications)
Buruli ulcer is an infection of the subcutaneous tissue leading to chronic necrotizing skin ulcers. Sub-Saharan Africa carries the main burden of BU, but it also occurs in the Americas and the Western
Beyond health-system building blocks: context and determinants of health (Publications)
The WHO health-system building block framework represents a construction that has been widely used to analyse health systems. While the framework has shown success and become a useful analytical tool,
