Genotyping methods to distinguish <em>Plasmodium falciparum</em> recrudescence from new infection for the assessment of antimalarial drug efficacy: an... (Publications)
BACKGROUND: Distinguishing Plasmodium falciparum recrudescence from new infections is crucial for the assessment of antimalarial drug efficacy against P falciparum. We aimed to compare the efficacy of
The non-inferiority of piperonyl-butoxide Yorkool® G3 insecticide-treated nets compared to Olyset®Plus measured by <em>Anopheles arabiensis</em>... (Publications)
BACKGROUND: Non-inferiority trials are recommended by the World Health Organization (WHO) to demonstrate that health products show comparable efficacy to that of existing standard of care. As part of
Single-dose drug development candidate for schistosomiasis (Publications)
Aryl hydantoins were identified in the early 1980s as a promising antischistosomal chemotype. However, as exemplified by Ro 13-3978, this compound series produced antiandrogenic side effects on the ho
Community-based type 2 diabetes care by lay village health workers in rural Lesotho: protocol for a cluster-randomized trial within the ComBaCaL... (Publications)
BACKGROUND: Type 2 diabetes (T2D) poses a growing public health burden, especially in low- and middle-income countries (LMICs). Task-shifting to lay village health workers (VHWs) and the use of digita
Baseline liver ultrasound findings in preschool children from the praziquantel in preschoolers trial in Lake Albert, Uganda (Publications)
BACKGROUND: Periportal fibrosis is a late-stage manifestation of chronic infection with Schistosoma mansoni. Praziquantel (PZQ), the only drug available for the treatment of schistosomiasis, has limit
Spatial distributions of diarrheal cases in relation to housing conditions in informal settlements: a cross-sectional study in Abidjan, Côte... (Publications)
In addition to individual practices and access to water, sanitation, and hygiene (WASH) facilities, housing conditions may also be associated with the risk of diarrhea. Our study embraced a broad appr
Vaccine value profile for leishmaniasis (Publications)
Leishmania infections are global, occurring in 98 countries and all World Health Organization (WHO) regions with 600 million to 1 billion people at risk of infection. Visceral leishmaniasis is associa
Unveiling maternal health insights during the COVID-19 pandemic in Pakistan: using causal loop diagrams to illuminate and prevent unintended policy... (Publications)
The authors explain that using causal loop diagrams can visualize retrospectively the unintended negative consequences of COVID-19 related policies on maternal health and has potential to be used pros