Novel antimalarial tetrazoles and amides active against the hemoglobin degradation pathway in <em>Plasmodium falciparum</em> (Publications)
Malaria control programs continue to be threatened by drug resistance. To identify new antimalarials, we conducted a phenotypic screen and identified a novel tetrazole-based series that shows fast-kil
International, transdisciplinary, and ecohealth action for sustainable agriculture in Asia (Publications)
Sustainably intensifying agriculture to secure food for people, while minimizing the human, animal, and environmental health impacts is an unprecedented global food security challenge. Action research
Animal presence modulates frontal brain activity of patients in a minimally conscious state: a pilot study (Publications)
Integrating animals into therapy is applied increasingly in patients in a minimally conscious state (MCS). This pilot study investigates the effect of animal presence on frontal brain activity in MCS
Evidence-based interventions to reduce mortality among preterm and low-birthweight neonates in low-income and middle-income countries: a systematic... (Publications)
BACKGROUND: Preterm birth is the leading cause of under-five-mortality worldwide, with the highest burden in low-income and middle-income countries (LMICs). The aim of this study was to synthesise evi
Association of incomplete adherence to antiretroviral therapy with cardiovascular events and mortality in virologically suppressed persons with HIV:... (Publications)
Background: Incomplete antiretroviral therapy (ART) adherence, even if sufficient to maintain viral suppression, is associated with enhanced inflammation in persons with HIV (PWH). However, its clinic
Predicting the impact of COVID-19 interruptions on transmission of <em>gambiense </em>human African trypanosomiasis in two health zones of the... (Publications)
Many control programmes against neglected tropical diseases have been interrupted due to the coronavirus disease 2019 (COVID-19) pandemic, including those that rely on active case finding. In this stu
Extensive drug resistance during low-level HIV viraemia while taking NNRTI-based ART supports lowering the viral load threshold for regimen switch in... (Publications)
OBJECTIVES: WHO guidelines on ART define the HIV-1 viral load (VL) threshold for treatment failure at 1000 copies/mL. The Switch Either near Suppression Or THOusand (SESOTHO) trial, conducted in Lesot
Hitzebedingte Sterblichkeit im Sommer 2019 (Publications)
Der Sommer 2019 gilt als drittheissester Sommer seit Messbeginn in der Schweiz. Zwei intensive Hitzewellen mit einer mittleren Maximaltemperatur von 32–34°C prägten die Monate Juni und Juli 2019. Inwi