Investigations of the metabolites of the trypanocidal drug melarsoprol (Publications)
BACKGROUND: Melarsoprol remains the first-choice drug for trypanosomiasis (human African sleeping sickness). To contribute to the sparse pharmacologic data and to better understand the cause of the fr
Effectiveness and acceptance of group therapy as a mental health intervention for people living with HIV in Africa - a scoping literature review (Publications)
Mental health problems are highly prevalent among people living with HIV/AIDS (PLWHA), yet mental health care in African countries is scarce. There is growing interest in understanding the effect of g
Swiss TPH: 30 years of R&D towards new drugs for tropical diseases (Publications)
The year 2023 marks the 80th anniversary of the Swiss Tropical and Public Health Institute (Swiss TPH). Associated with the University of Basel, Swiss TPH combines research, education and services, wo
Cross-sectional surveys and subtype classification of human <em>Blastocystis</em> isolates from four epidemiological settings in China (Publications)
The prevalence and geographical distribution of the intestinal protozoa Blastocystis in humans across China is unknown, and the relative importance of different subtypes has yet to be investigated. We
Quantification of self pollution from two diesel school buses using three independent methods (Publications)
We monitored two Seattle school buses to quantify the buses' self pollution using the dual tracers (DT), lead vehicle (LV), and chemical mass balance (CMB) methods. Each bus drove along a residential
Parallel synthesis of a series of non-functional ATP/NAD analogs with activity against trypanosomatid parasites (Publications)
Non-functional analogs of the cofactors ATP and NAD are putative inhibitors of ATP- or NAD-dependant enzymes. Since pathogenic protozoa rely heavily on the salvage of purine nucleosides from the blood
