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1. Phylogenomics of <em>Mycobacterium africanum</em> reveals a new lineage and a complex evolutionary history (Publications)

   Phylogenomics of <em>Mycobacterium africanum</em> reveals a new lineage and a complex evolutionary history

   Pertinence:

   Human tuberculosis (TB) is caused by members of the Mycobacterium tuberculosis complex (MTBC). The MTBC comprises several human-adapted lineages known as M. tuberculosis sensu stricto, as well as two

2. Assessment of fecal calprotectin and fecal occult blood as point-of-care markers for soil-transmitted helminth attributable intestinal morbidity in a... (Publications)

   Assessment of fecal calprotectin and fecal occult blood as point-of-care markers for soil-transmitted helminth attributable intestinal morbidity in a case-control substudy conducted in Côte d'Ivoire, Lao PDR and Pemba Island, Tanzania

   Pertinence:

   Background: Infections with soil-transmitted helminths (STHs) may result in chronic inflammatory disorders affecting the human host. The objective of this study was to evaluate Fecal Calprotectin (FC)

3. Initial characterisation of commercially available ELISA tests and the immune response of the clinically correlated SARS-CoV-2 biobank... (Publications)

   Initial characterisation of commercially available ELISA tests and the immune response of the clinically correlated SARS-CoV-2 biobank “SERO-BL-COVID-19” collected during the pandemic onset in Switzerland

   Pertinence:

   Background To accurately measure seroprevalance in the population, both the expected immune response as well as the assay performances have to be well characterised. Here, we describe the collection a

4. An interdisciplinary centre of excellence for pastoralists in the Horn of Africa (Publications)

   An interdisciplinary centre of excellence for pastoralists in the Horn of Africa

   Pertinence:

   The specific needs of nomadic pastoralist communities are often not considered in public services. This is also the case in the health sector. In Ethiopia, Swiss Development Cooperation is supporting

5. One Health - towards a more inclusive science (Publications)

   One Health - towards a more inclusive science

   Pertinence:

   How can we move in the direction of a modern theory of health that has the ability to face the new complex challenges of global change? The One Health concept suggests that health must be viewed as th

6. Rollout of dolutegravir-based antiretroviral therapy in sub-Saharan Africa and its public health implications (Publications)

   Rollout of dolutegravir-based antiretroviral therapy in sub-Saharan Africa and its public health implications

   Pertinence:

7. Optimization of benzothiazole and thiazole hydrazones as inhibitors of schistosome bcl-2a (Publications)

   Optimization of benzothiazole and thiazole hydrazones as inhibitors of schistosome bcl-2a

   Pertinence:

   Limited therapeutic options are available for the treatment of human schistosomiasis caused by the parasitic Schistosoma flatworm. The B cell lymphoma-2 (BCL-2)-regulated apoptotic cell death pathway

8. DaFFür Berlin : Perspektiven für Deutsch als Fremd- und Zweitsprache in Schule, Beruf und Wissenschaft: 44. Jahrestagung des Fachverbandes Deutsch als... (Publications)

   DaFFür Berlin : Perspektiven für Deutsch als Fremd- und Zweitsprache in Schule, Beruf und Wissenschaft: 44. Jahrestagung des Fachverbandes Deutsch als Fremd- und Zweitsprache an der Technischen Universität Berlin 2017

   Pertinence:

9. Quest for a potent antimalarial drug lead: synthesis and evaluation of 6,7-dimethoxyquinazoline-2,4-diamines (Publications)

   Quest for a potent antimalarial drug lead: synthesis and evaluation of 6,7-dimethoxyquinazoline-2,4-diamines

   Pertinence:

   Quinazolines have long been known to exert varied pharmacologic activities that make them suitable for use in treating hypertension, viral infections, tumors, and malaria. Since 2014, we have synthesi

10. Parasite-host dynamics throughout antimalarial drug development stages complicate the translation of parasite clearance (Publications)

    Parasite-host dynamics throughout antimalarial drug development stages complicate the translation of parasite clearance

    Pertinence:

    Ensuring continued success against malaria depends on a pipeline of new antimalarials. Antimalarial drug development utilizes pre-clinical murine and experimental human malaria infection studies to ev