Impact of seven years of mass drug administration and recrudescence of <em>Schistosoma haematobium</em> infections after one year of treatment gap in... (Publications)
BACKGROUND: Considerable progress towards the elimination of urogenital schistosomiasis was made by the Zanzibar Elimination of Schistosomiasis Transmission project from 2012 till 2016, when biannual
The shift from inpatient care to outpatient care in Switzerland since 2017: policy processes and the role of evidence (Publications)
The shift from inpatient care to the ambulatory sector is a central aspiration of European health systems. Despite demonstrated benefits, health reforms have struggled to realize their potential. In t
Modelling the impact of COVID-19-related programme interruptions on visceral leishmaniasis in India (Publications)
BACKGROUND: In March 2020, India declared a nationwide lockdown to control the spread of coronavirus disease 2019. As a result, control efforts against visceral leishmaniasis (VL) were interrupted. ME
Health impact assessment of a watershed development project in southern India: a case study (Publications)
A “Health in All” approach has been encouraged by India’s National Health Policy to address cross-sectoral health concerns. To illustrate how health concerns can be systematised in food system plannin
Identification and profiling of a novel diazaspiro[3.4]octane chemical series active against multiple stages of the human malaria parasite... (Publications)
A novel diazaspiro[3.4]octane series was identified from a Plasmodium falciparum whole-cell high-throughput screening campaign. Hits displayed activity against multiple stages of the parasite lifecycl
Cost-effectiveness modelling to optimise active screening strategy for <em>gambiense </em>human African trypanosomiasis in endemic areas of the... (Publications)
BACKGROUND: Gambiense human African trypanosomiasis (gHAT) has been brought under control recently with village-based active screening playing a major role in case reduction. In the approach to elimin
Structural basis of malaria RIFIN binding by LILRB1-containing antibodies (Publications)
Some Plasmodium falciparum repetitive interspersed families of polypeptides (RIFINs)—variant surface antigens that are expressed on infected erythrocytes1—bind to the inhibitory receptor LAIR1, and in
Validation of a human-serum-based <em>in vitro </em>growth method for drug screening on juvenile development stages of <em>Schistosoma mansoni</em> (Publications)
BACKGROUND: Schistosomiasis affects over 200 million people worldwide but only praziquantel is available for treatment and control. Drug discovery is often based on phenotypic drug screening, involvin
The long-term impact of the Leprosy Post-Exposure Prophylaxis (LPEP) program on leprosy incidence: a modelling study (Publications)
BACKGROUND: The Leprosy Post-Exposure Prophylaxis (LPEP) program explored the feasibility and impact of contact tracing and the provision of single dose rifampicin (SDR) to eligible contacts of newly
Estimating true prevalence of <em>Schistosoma mansoni</em> from population summary measures based on the Kato-Katz diagnostic technique (Publications)
BACKGROUND: The prevalence of Schistosoma mansoni infection is usually assessed by the Kato-Katz diagnostic technique. However, Kato-Katz thick smears have low sensitivity, especially for light infect
