Chemically diverse <em>S. mansoni</em> HDAC8 inhibitors reduced viability in worm larval and adult stages (Publications)
Schistosoma mansoni HDAC8 is a reliable target to fight schistosomiasis, and several inhibitors have been reported in the literature up to now. Nevertheless, only a few displayed selectivity over the
Integrating statistical and agent-based modelling for activity-based ambient air pollution exposure assessment (Publications)
Assessment of long-term human exposure to spatiotemporally highly variable air pollution requires accounting for human space–time activity. Individual exposure and space–time track data are not availa
Bayesian spatio-temporal modelling of air pollution burden in Europe: integrating data from monitors, satellites and chemical transport models (Publications)
Ambient air quality is a growing global public health concern. Reducing air pollution and its burden on health is the aim of several environmental agencies and global agendas including the sustainable
Assessment of water, sanitation, and hygiene services in district health care facilities in rural area of Mekong delta, Vietnam (Publications)
Access to sufficient water, sanitation, and hygiene (WASH) services is a crucial requirement for patients during therapy and general well-being in the hospital. However, in low- and middle-income coun
Screening open access compound libraries and repurposing drugs to identify and characterize new molecules active against schistosomiasis and other... (Publications)
Far from the baneful impact of the so-called “big three” (HIV/AIDS, tuberculosis and malaria), schistosomiasis and other worm infections, such as the soil-transmitted helminths (STH) for example, have
Long-term exposure to air pollution and mortality from dementia, psychiatric disorders, and suicide in a large pooled European cohort: ELAPSE study (Publications)
Ambient air pollution is an established risk factor for premature mortality from chronic cardiovascular, respiratory and metabolic diseases, while evidence on neurodegenerative diseases and psychiatri
Glyphosate and AMPA in human urine of HBM4EU-aligned studies: part B adults (Publications)
Within HBM4EU, human biomonitoring (HBM) studies measuring glyphosate (Gly) and aminomethylphosphonic acid (AMPA) in urine samples from the general adult population were aligned and quality-controlled
Human exposure to pesticides in dust from two agricultural sites in South Africa (Publications)
Over the last decades, concern has arisen worldwide about the negative impacts of pesticides on the environment and human health. Exposure via dust ingestion is important for many chemicals but poorly
Antiprotozoal activity of azabicyclo-nonanes linked to tetrazole or sulfonamide cores (Publications)
N-(Aminoalkyl)azabicyclo[3.2.2]nonanes possess antiplasmodial and antitrypanosomal activity. A series with terminal tetrazole or sulfonamido partial structure was prepared. The structures of all new c