Fexinidazole for human African trypanosomiasis, the fruit of a successful public-private partnership (Publications)
After 100 years of chemotherapy with impractical and toxic drugs, an oral cure for human African trypanosomiasis (HAT) is available: Fexinidazole. In this case, we review the history of drug discovery
Optimizing implementation of preventive chemotherapy against soil-transmitted helminthiasis and intestinal schistosomiasis using high-resolution data:... (Publications)
BACKGROUND: Despite efforts to control neglected tropical diseases (NTDs) using preventive chemotherapy (PC), soil-transmitted helminthiases and schistosomiasis remain widely prevalent in sub-Saharan
Short-, mid-, and long-term epidemiological and economic effects of the World Bank Loan Project on schistosomiasis control in the People's Republic of... (Publications)
It is widely acknowledged that the 10-year World Bank Loan Project (WBLP) on schistosomiasis control in the People's Republic of China played an important role in raising the public and political prof
The Chronic Diseases Clinic of Ifakara (CDCI): establishing a model clinic for chronic care delivery in rural sub-Saharan Africa (Publications)
The rollout of antiretroviral drugs in sub-Saharan Africa to address the huge health impact of the HIV pandemic has been one of the largest projects undertaken in medical history and is an unprecedent
Accelerated development of malaria monoclonal antibodies (Publications)
L9LS, a potent and safe antimalarial monoclonal antibody, demonstrated 88% protective efficacy against infection in a phase 1 trial in healthy adults.(1) These promising results are the first of many
Pre-treatment HIV-1 drug resistance in antiretroviral therapy-naive adults in Eastern Africa: a systematic review and meta-analysis (Publications)
BACKGROUND: Pre-treatment HIV drug resistance (PDR) may result in increased risk of virological failure and acquisition of new resistance mutations. With recently increasing ART coverage and periodic
Containment of a fatal and highly infectious disease outbreak (Publications)
This case study was designed based on several experience with several viral haemorrhagic fevers (VHFs) outbreaks responded to in Uganda between 2000 and 2016. Fictitious scenarios have been included t
Work time allocation at primary health care level in two regions of Albania (Publications)
INTRODUCTION: Although well-performing workforce is essential to equitable and efficient health service delivery, few countries have systematically addressed performance improvements. How health worke
Molecular epidemiology of tuberculosis in the Somali region, eastern Ethiopia (Publications)
Background: Tuberculosis (TB) is one of the leading causes of morbidity and mortality in low-income countries like Ethiopia. However, because of the limited laboratory infrastructure there is a shorta