HIV coinfection is associated with low fitness <em>rpoB</em> variants in rifampicin-resistant <em>Mycobacterium tuberculosis</em> (Publications)
We analysed 312 drug-resistant genomes of Mycobacterium tuberculosis (Mtb) collected from HIV coinfected and HIV negative TB patients from nine countries with a high tuberculosis burden. We found that
Non-invasive monitoring of drug action: a new live <em>in vitro</em> assay design for Chagas' disease drug discovery (Publications)
New assay designs are needed to improve the predictive value of the Trypanosoma cruzi in vitro tests used as part of the Chagas' disease drug development pipeline. Here, we employed a green fluorescen
Travel patterns, risk behaviour and health problems of travellers with rheumatic diseases compared to controls: a multi-centre, observational study (Publications)
BACKGROUND: Patients with chronic conditions travel around the world more than ever. Only few studies have examined travel patterns and health outcomes of patients with rheumatic diseases during inter
Incorporating operational research in programmes funded by the Global Fund to Fight AIDS, Tuberculosis and Malaria in four sub-Saharan African... (Publications)
BACKGROUND: The current study builds upon a previous situation analysis of the extent to which grants from the Global Fund to Fight AIDS, Tuberculosis and Malaria (Global Fund) are being utilized to s
Population genomics of two invasive mosquitoes (<em>Aedes aegypti </em>and <em>Aedes albopictus</em>) from the Indo-Pacific (Publications)
The arbovirus vectors Aedes aegypti (yellow fever mosquito) and Ae. albopictus (Asian tiger mosquito) are both common throughout the Indo-Pacific region, where 70% of global dengue transmission occurs
Patterns of pesticide usage in agriculture in rural Tanzania call for integrating agricultural and public health practices in managing... (Publications)
BACKGROUND: Unrestricted use of pesticides in agriculture is likely to increase insecticide resistance in mosquito vectors. Unfortunately, strategies for managing insecticide resistance in agriculture
PfMAP-2 is essential for male gametogenesis in the malaria parasite<em> Plasmodium falciparum</em> (Publications)
In malaria parasites, male gametogenesis is a proliferative stage essential for parasite transmission to the mosquito vector. It is a rapid process involving three rounds of genome replication alterna
Naturally occurring cardenolides affecting <em>Schistosoma mansoni</em> (Publications)
Schistosomiasis is a neglected tropical disease of considerable public health burden. We recently discovered a micromolar activity of several cardenolides against newly transformed schistosomula (NTS)
<em>Opisthorchis felineus</em> infection, risks, and morbidity in rural Western Siberia, Russian Federation (Publications)
BACKGROUND: The liver fluke, Opisthorchis felineus, is widely distributed throughout Europe and large parts of the Russian Federation. In Western Siberia, information about opisthorchiasis is lacking
The independent association of source-specific transportation noise exposure, noise annoyance and noise sensitivity with health-related quality of... (Publications)
Noise exposure is affecting health-related quality of life (HRQoL). There are many modelling approaches linking specific noise sources with single health-related outcomes. However, an integrated appro
