Occupational exposure and the risk of airway obstruction and mortality (Publications)
OBJECTIVES: To identify occupational groups at high risk of airway obstruction (AO) and mortality and potential interactions with smoking. METHODS: Lung function data from the LuftiBus project were en
Malaria infection prevalence and sensitivity of reactive case detection in Zanzibar (Publications)
BACKGROUND: Reactive case detection (RCD) is a commonly used strategy for malaria surveillance and response in elimination settings. Many approaches to RCD assume detectable infections are clustered w
‘The time where the British took the lead is over’: ethical aspects of writing in complex research partnerships (Publications)
Writing reflects some of the different characteristics of the language being used and of the people who are communicating. The present paper focusses on the internal written communication in internati
Antenatal care service delivery and factors affecting effective tetanus vaccine coverage in low- and middle-income countries: results of the Maternal... (Publications)
OBJECTIVES: To map the integration of existing maternal tetanus immunization programmes within antenatal care (ANC) services for pregnant women in low- and middle-income countries (LMICs) and to ident
A sister lineage of the <em>Mycobacterium tuberculosis </em>complex discovered in the African Great Lakes region (Publications)
The human- and animal-adapted lineages of the Mycobacterium tuberculosis complex (MTBC) are thought to have expanded from a common progenitor in Africa. However, the molecular events that accompanied
Point-of-care ultrasound: a useful diagnostic tool in Africa (Publications)
In resource limited settings with limited tests and diagnostic tools, most of diagnoses are based on clinical findings, and patients are managed empirically, e.g. with anti-tuberculosis drugs. This ar
Characterization of a defensin from the sand fly <em>Phlebotomus duboscqi</em> induced by challenge with bacteria or the protozoan parasite... (Publications)
Antimicrobial peptides are major components of the innate immune response of epithelial cells. In insect vectors, these peptides may play a role in the control of gut pathogens. We have analyzed antim
Epithelial innate immunity. A novel antimicrobial peptide with antiparasitic activity in the blood-sucking insect<em> Stomoxys calcitrans</em> (Publications)
The gut epithelium is an essential interface in insects that transmit parasites. We investigated the role that local innate immunity might have on vector competence, taking Stomoxys calcitrans as a mo
Ancistrotanzanine C and related 5,1'- and 7,3'-coupled naphthylisoquinoline alkaloids from <em>Ancistrocladus tanzaniensis</em> (Publications)
Three new naphthylisoquinoline alkaloids, the 7,3'-coupled ancistrotanzanine C (6), the 5,1'-coupled O-methylancistrocladinine (7), and the likewise 5,1'-coupled O,N-dimethylancistrocladine (8, previo
Synthesis and antiprotozoal activities of simplified analogs of naphthylisoquinoline alkaloids (Publications)
The naphthylisoquinoline alkaloids (NIQs) represent a class of natural products with manifold activities against various tropical diseases. They are isolated from rare and difficult-to-cultivate tropi
