Pumilanol, an antiprotozoal isoflavanol from Tephrosia pumila47 (Publications)
A novel isoflavan-4-ol (pumilanol), (rel)-3 beta-(2'-hydroxy-4',5'-methylenedioxyphenyl)-6-methoxy-4 alpha,7-dihydroxybenzo-3,4-dihydropyran (1) and two known flavonoids, tephrinone (2) and rotenone (
Variable host-pathogen compatibility in <em>Mycobacterium tuberculosis</em> (Publications)
Mycobacterium tuberculosis remains a major cause of morbidity and mortality worldwide. Studies have reported human pathogens to have geographically structured population genetics, some of which have b
The competitive cost of antibiotic resistance in <em>Mycobacterium tuberculosis</em> (Publications)
Mathematical models predict that the future of the multidrug-resistant tuberculosis epidemic will depend on the fitness cost of drug resistance. We show that in laboratory-derived mutants of Mycobacte
Global phylogeography of <em>Mycobacterium tuberculosis</em> and implications for tuberculosis product development (Publications)
New tools for controlling tuberculosis are urgently needed. Despite our emerging understanding of the biogeography of Mycobacterium tuberculosis, the implications for development of new diagnostics, d
Joziknipholones A and B: the first dimeric phenylanthraquinones from the roots of <em>Bulbine frutescens</em> (Publications)
From the roots of the African plant Bulbine frutescens (Asphodelaceae), two unprecedented novel dimeric phenylanthraquinones, named joziknipholones A and B, possessing axial and centrochirality, were
Ancistrocladinium A and B, the first N,C-coupled naphthyldihydroisoquinoline alkaloids, from a Congolese ancistrocladus species (Publications)
The isolation and structural elucidation of three novel-type naphthylisoquinoline alkaloids, ancistrocladinium A and B (the latter along with its atropisomer), from a Congolese Ancistrocladus species
The creation of an indicator for the health effect of air pollutants (Publications)
The department of social and preventive medicine of the University of Basle is conducting an epidemiologic study on the health effect of air pollution on preschool children. Nitrogen dioxide in childr