Epimers of bicyclo[2.2.2]octan-2-ol derivatives with antiprotozoal activity (Publications)
(2SR,6RS,7RS)-4-Dialkylaminobicyclo[2.2.2]octan-2-ols and several of their esters have shown promising activity against the causative organisms for malaria and sleeping sickness. The base-catalyzed ep
Rapid one-pot synthesis of antiparasitic quinolines based upon the microwave-assisted coupling-isomerization reaction (MACIR) (Publications)
2-Substituted quinolines and related derivatives can be rapidly prepared from (hetero)aryl halides and propargyl alcohols in the sense of a one-pot microwave-assisted coupling-isomerization reaction (
An entomopathogenic fungus for control of adult African malaria mosquitoes (Publications)
Biological control of malaria mosquitoes in Africa has rarely been used in vector control programs. Recent developments in this field show that certain fungi are virulent to adult Anopheles mosquitoes
Isomerization of 4-amino-6,7-diphenylbicyclo[2.2.2]octan-2-ones (Publications)
Under strongly basic conditions (6SR,7SR)-4-amino-6,7-diphenylbicyclo[2.2.2]octan-2-ones isomerized regioselectively in position 6 giving their (6RS,7SR) analogues. The structure of the new products w
New 4-amino-2-azabicyclo[3.2.2]nonane derivatives and their antiprotozoal potencies (Publications)
Several 2-substituted 4-amino-2-azabicyclo [3.2.2]nonane derivatives were synthesized. The new compounds were investigated for their activities against the causative organism of East African sleeping
New derivatives of 4-aminobicyclo[2.2.2]octanones and -ols as potential antiprotozoals (Publications)
New derivatives of 4-aminobicyclo[2.2.2]octanones and -ols were prepared. Their structures were established by means of NMR experiments. All new compounds were tested for their activities against Plas