Analysis of the physicochemical properties of anti-schistosomal compounds to identify next-generation leads (Publications)
To investigate the physicochemical properties of anti-schistosomal compounds reported between 2008 and 2023, a simple but extensive literature scrutiny was conducted. Keywords were searched in Chemica
Evaluating and enhancing an educational intervention to reduce smallholder farmers' exposure to pesticides in Uganda through a digital, systematic... (Publications)
BACKGROUND: Smallholder farmers receive educational interventions on safe pesticide handling by governmental agencies, industries, or nongovernmental organizations to reduce exposure risks. However, e
Rapid detection of the source of a <em>Listeria monocytogenes</em> outbreak in Switzerland through routine interviewing of patients and whole-genome... (Publications)
AIMS OF THE STUDY: Listeriosis is a notifiable disease in Switzerland. In summer 2022, the Swiss Federal Office of Public Health noticed an increase in reports of listeriosis cases, indicating a possi
Temperature frequency and mortality: assessing adaptation to local temperature (Publications)
Assessing the association between temperature frequency and mortality can provide insights into human adaptation to local ambient temperatures. We collected daily time-series data on mortality and tem
Social Transfers for Exclusive Breastfeeding (STEB) Intervention in Lao People's Democratic Republic: protocol for a randomized controlled trial (Publications)
BACKGROUND: Children in Lao People's Democratic Republic (Lao PDR) receive suboptimal nutrition because of low breastfeeding rates, undermining their developmental potential. While major public health
HIV co-infection is associated with reduced <em>Mycobacterium tuberculosis</em> transmissibility in sub-Saharan Africa (Publications)
Persons living with HIV are known to be at increased risk of developing tuberculosis (TB) disease upon infection with Mycobacterium tuberculosis (Mtb). However, it has remained unclear how HIV co-infe
On-target, dual aminopeptidase inhibition provides cross-species antimalarial activity (Publications)
To combat the global burden of malaria, development of new drugs to replace or complement current therapies is urgently required. Here, we show that the compound MMV1557817 is a selective, nanomolar i
Psychophysiological effects of walking in forests and urban built environments with disparate road traffic noise exposure: study protocol of a... (Publications)
BACKGROUND: Stress is a widespread phenomenon and reality of everyday life, entailing negative consequences for physical and psychological wellbeing. Previous studies have indicated that exposure to g
Identification of a family of species-selective complex I inhibitors as potential anthelmintics (Publications)
Soil-transmitted helminths (STHs) are major pathogens infecting over a billion people. There are few classes of anthelmintics and there is an urgent need for new drugs. Many STHs use an unusual form o