Antibiotics in pregnancy influence nasal microbiome and respiratory morbidity in infancy (Publications)
BACKGROUND: The effects of prenatal antibiotic exposure on respiratory morbidity in infancy and the involved mechanisms are still poorly understood. We aimed to examine whether prenatal antibiotic exp
Macrophage susceptibility to infection by Ghanaian <em>Mycobacterium tuberculosis</em> complex lineages 4 and 5 varies with self-reported ethnicity (Publications)
BACKGROUND: The epidemiology of Mycobacterium tuberculosis complex (MTBC) lineage 5 (L5) infections in Ghana revealed a significantly increased prevalence in Ewes compared to other self-reported ethni
Testing and treatment for malaria elimination: a systematic review (Publications)
BACKGROUND: Global interest in malaria elimination has prompted research on active test and treat (TaT) strategies. METHODS: A systematic review and meta-analysis were conducted to assess the effectiv
Risk of imported malaria infections in Zanzibar: a cross-sectional study (Publications)
BACKGROUND: Zanzibar has made substantial progress in malaria control with vector control, improved diagnosis, and artemisinin-based combination therapy. Parasite prevalence in the population has rema
Guillain-Barré syndrome associated with hepatitis E virus infection: a case report (Publications)
KEY CLINICAL MESSAGE: Hepatitis E virus (HEV) infection can be manifested with several neurological syndromes including GBS. Therefore, healthcare providers should consider HEV in their differential d
Whole-genome sequencing for One Health surveillance of antimicrobial resistance in conflict zones: a case study of <em>Salmonella</em> spp. and... (Publications)
Antimicrobial resistance (AMR) is a critical global concern driven by the overuse, misuse, and/or usage of inadequate antibiotics on humans, animals' agriculture, and as a result of contaminated envir
Health system performance and resilience in times of crisis: an adapted conceptual framework (Publications)
With the COVID-19 pandemic, the notion of health system (HS) performance has been discussed, and the notion of resilience has become increasingly important. Lacking a recognised framework that measure
Efficacy of the spatial repellent product Mosquito Shield™ against wild pyrethroid-resistant <em>Anopheles arabiensis</em> in south-eastern Tanzania (Publications)
BACKGROUND: Spatial repellents that create airborne concentrations of an active ingredient (AI) within a space offer a scalable solution to further reduce transmission of malaria, by disrupting mosqui
Effect of compensatory evolution in the emergence and transmission of rifampicin-resistant <em>Mycobacterium tuberculosis </em>in Cape Town, South... (Publications)
BACKGROUND: Experimental data show that drug-resistance-conferring mutations are often associated with a decrease in the replicative fitness of bacteria in vitro, and that this fitness cost can be mit
Association of long-term exposure to ambient air pollution with retinal neurodegeneration: the prospective Alienor study (Publications)
Chronic exposure to air pollution may have adverse effects on neurodegenerative diseases. Glaucoma, the second leading cause of blindness worldwide, is a neurodegenerative disease of the optic nerve,
