Understanding drug exposure and <em>Trichuris trichiura</em> cure rates: a pharmacometric approach for albendazole-ivermectin co-medication in... (Publications)
BACKGROUND AND OBJECTIVE: Trichuriasis caused by the human whipworm Trichuris trichiura poses a significant public health concern. Albendazole-ivermectin co-medication is currently the most effective
Optimization of pyrazolopyridine 4-carboxamides with potent antimalarial activity for which resistance is associated with the <em>P. falciparum</em>... (Publications)
Emerging resistance to current antimalarials is reducing their effectiveness and therefore there is a need to develop new antimalarial therapies. Toward this goal, high throughput screens against the
Low tuberculosis treatment initiation after positive tuberculosis lipoarabinomannan results (Publications)
A positive urine TB-LAM result should lead to TB treatment initiation. TB treatment uptake was low after a positive TB-LAM but negative Xpert test. A lack of trust in TB-LAM results by clinicians and
A prospective evaluation of the diagnostic accuracy of the point-of-care VISITECT CD4 Advanced Disease test in seven countries (Publications)
BACKGROUND: CD4 measurement is pivotal in the management of advanced HIV disease. VISITECT® CD4 Advanced Disease (AccuBio Limited, Alva, UK; VISITECT) is an instrument-free, point-of-care, semi-quanti
Socioeconomic status and adherence to preventive measures during the COVID-19 pandemic in Switzerland: a population based digital cohort analysis (Publications)
OBJECTIVES: To assess the association between socioeconomic status (SES) and self-reported adherence to preventive measures in Switzerland during the COVID-19 pandemic. METHODS: 4,299 participants fro
Seasonal malaria chemoprevention and the spread of <em>Plasmodium falciparum </em>quintuple-mutant parasites resistant to sulfadoxine-pyrimethamine: a... (Publications)
BACKGROUND: Seasonal malaria chemoprevention (SMC) with sulfadoxine-pyrimethamine plus amodiaquine prevents millions of clinical malaria cases in children younger than 5 years in Africa's Sahel region
Evaluating double-duty actions in Rwanda's secondary cities (Publications)
The double burden of malnutrition (DBM) is escalating in low- and middle-income countries (LMICs), including in Rwanda, most notably in urbanizing areas. The 2019-2020 Rwanda Demographic Health Survey
TOLLIP and MUC5B modulate the effect of ambient NO(2) on respiratory symptoms in infancy (Publications)
BACKGROUND: Current knowledge suggests that the gene region containing MUC5B and TOLLIP plays a role in airway defence and airway inflammation, and hence respiratory disease. It is also known that exp
Cardiac involvement in Chagas disease and African trypanosomiasis (Publications)
Trypanosomiases are diseases caused by various species of protozoan parasite in the genus Trypanosoma, each presenting with distinct clinical manifestations and prognoses. Infections can affect multip
