Potential impact of climatic factors on malaria in Rwanda between 2012 and 2021: a time-series analysis (Publications)
BACKGROUND: Malaria remains an important public health problem, particularly in sub-Saharan Africa. In Rwanda, where malaria ranks among the leading causes of mortality and morbidity, disease transmis
Socioeconomic inequalities in the external exposome in european cohorts: the EXPANSE Project (Publications)
Socioeconomic inequalities in the exposome have been found to be complex and highly context-specific, but studies have not been conducted in large population-wide cohorts from multiple countries. This
Commentary: a road map for future data-driven urban planning and environmental health research (Publications)
Recent advances in data science and urban environmental health research utilise large-scale databases (100s–1000s of cities) to explore the complex interplay of urban characteristics such as city form
Temporal variations in the short-term effects of ambient air pollution on cardiovascular and respiratory mortality: a pooled analysis of 380 urban... (Publications)
BACKGROUND: Ambient air pollution, including particulate matter (such as PM(10) and PM(2·5)) and nitrogen dioxide (NO(2)), has been linked to increases in mortality. Whether populations' vulnerability
Reflex Xpert MTB/XDR testing of residual rifampicin-resistant specimens: a clinical laboratory-based diagnostic accuracy and feasibility study in... (Publications)
BACKGROUND: The World Health Organization-approved Xpert MTB/XDR test detects Mycobacterium tuberculosis and resistance to isoniazid, fluoroquinolones, ethionamide, and injectable drugs directly in sp
Optimising HIV spending in 12 eastern European and central Asian countries: a modelling study (Publications)
BACKGROUND: The eastern European and central Asian (EECA) region has the fastest growing HIV epidemic globally. We aimed to identify how HIV resources could be allocated for maximum health impact. MET
A novel barcoded nanopore sequencing workflow of high-quality, full-length bacterial 16S amplicons for taxonomic annotation of bacterial isolates and... (Publications)
Due to recent improvements, Nanopore sequencing has become a promising method for experiments relying on amplicon sequencing. We describe a flexible workflow to generate and annotate high-quality, ful
Burden of disease in Germany attributed to ambient particulate matter pollution : findings from the Global Burden of Disease Study 2019 (Publications)
INTRODUCTION: Ambient fine particulate matter pollution with a diameter less than 2.5 micrometers (PM(2.5)) is a significant risk factor for chronic noncommunicable diseases (NCDs), leading to a subst
Long-term results of hypofractionated radiotherapy with intra-prostatic boosts in men with intermediate- and high-risk prostate cancer: a phase II... (Publications)
AIMS: In the conventionally fractionated phase III FLAME prostate trial, focal boosts improved local control and biochemical disease-free survival (bDFS). We explored the toxicity and effectiveness of