Differences in conformational dynamics between <em>Plasmodium falciparum</em> and human Hsp90 orthologues enable the structure-based discovery of... (Publications)
The high sequence conservation of druggable pockets of closely related proteins can make it challenging to develop selective inhibitors. We designed a new drug discovery approach that exploits both th
Atopic conditions and brain tumor risk in children and adolescents: an international case-control study (CEFALO) (Publications)
BACKGROUND: A number of epidemiological studies indicate an inverse association between atopy and brain tumors in adults, particularly gliomas. We investigated the association between atopic disorders
A profile of travelers - an analysis from a large Swiss travel clinic (Publications)
BACKGROUND: Globally, the Swiss have one of the highest proportions of the population traveling to tropical and subtropical countries. Large travel clinics serve an increasing number of customers with
Paraspinal abscess secondary to tuberculous spondylitis diagnosed by Xpert MTB/RIF assay in rural Tanzania (Publications)
A 31-year-old HIV-negative man presented to our clinic with a 6-month history of back pain and a swelling at the back. Radiological studies revealed lumbar vertebral destruction. Ultrasound of the mas
Evidence for diversifying selection in a set of <em>Mycobacterium tuberculosis</em> genes in response to antibiotic- and nonantibiotic-related... (Publications)
Tuberculosis (TB) is a global health problem estimated to kill 1.4 million people per year. Recent advances in the genomics of the causative agents of TB, bacteria known as the Mycobacterium tuberculo
Epidemiology of malaria in the Papua New Guinean highlands (Publications)
Objectives To conduct an in-depth investigation of the epidemiology of malaria in the Papua New Guinea (PNG) highlands and provide a basis for evidence-based planning and monitoring of intensified mal
Epidemiology of <em>Plasmodium falciparum</em> gametocytemia in India: prevalence, age structure, risk factors and the role of a predictive score for... (Publications)
OBJECTIVE: To characterise the epidemiology of Plasmodium falciparum gametocytemia and determine the prevalence, age structure and the viability of a predictive model for detection. METHODS: We collec
Zahnverlust, prothetische Versorgung und zahnärztliche Inanspruchnahme in der Schweiz (Publications)
The aim of this study is to report about the dental health situation in Switzerland and to evaluate frequencies of dental visits. Data were obtained from the first and second national Health Survey of
