<em>Plasmodium falciparum</em> and <em>Plasmodium vivax</em> genotypes and efficacy of intermittent preventive treatment in Papua New Guinea (Publications)
Intermittent preventive treatment of infants (IPTi) reduces early-childhood malaria-related morbidity. While genotypic drug resistance markers have proven useful in predicting the efficacy of antimala
<em>In vitro</em> and<em> In vivo</em> evaluation of 28DAP010, a novel diamidine for treatment of second-stage African sleeping sickness (Publications)
African sleeping sickness is a neglected tropical disease transmitted by tsetse flies. New and better drugs are still needed especially for its second stage, which is fatal if untreated. 28DAP010, a d
Helminth products bypass the need for TSLP in Th2 immune responses by directly modulating dendritic cell function (Publications)
Thymic stromal lymphopoietin (TSLP) is an interleukin (IL)-7-like cytokine, mainly expressed by epithelial cells, and key to the development of allergic responses. The well-documented involvement of T
Lipidomics identifies a requirement for peroxisomal function during influenza virus replication (Publications)
Influenza virus acquires a host-derived lipid envelope during budding, yet a convergent view on the role of host lipid metabolism during infection is lacking. Using a mass spectrometry-based lipidomic
Hydroxyurea: effect on growth, structure, and [3H]thymidine uptake of <em>Trypanosoma brucei</em> procyclic culture forms (Publications)
Hydroxyurea (HU) in concentrations above 50 micrograms/ml reversibly inhibited cell division of Trypanosoma brucei brucei stock STIB 336 procyclic culture forms, but not growth of individual cells. Th
Effect of temperature on the development of <em>Schistosoma japonicum</em> within <em>Oncomelania hupensis</em>, and hibernation of <em>O.... (Publications)
The objectives of this investigation were to assess the effect of temperature on the development of Schistosoma japonicum harboured in Oncomelania hupensis and to determine the lowest temperature thre