Directed synthesis of all four pure stereoisomers of the <em>N,C</em>-Coupled naphthylisoquinoline alkaloid ancistrocladinium A (Publications)
The first preparation of the N,C-coupled naphthylisoquinoline alkaloid ancistrocladinium A and its likewise naturally occurring minor atropisomer, in an atropisomerically pure form, is described. The
Validating the children's depression inventory in the context of Rwanda (Publications)
BACKGROUND: Depression is often co-morbid with chronic conditions, and when combined with HIV it can increase progression and reduce survival. A brief and accurate screening tool for depression among
Benefits and limitations of a community-engaged emergency referral system in a remote, impoverished setting of northern Ghana (Publications)
Although Ghana has a well-organized primary health care system, it lacks policies and guidelines for developing or providing emergency referral services. In 2012, an emergency referral pilot-the Susta
Comparison of molecular quantification of <em>Plasmodium falciparum</em> gametocytes by <em>Pfs</em>25 qRT-PCR and QT-NASBA in relation to mosquito... (Publications)
BACKGROUND: Quantifying gametocyte densities in natural malaria infections is important to estimate malaria transmission potential. Two molecular methods (Pfs25 mRNA quantitative reverse transcriptase
Urogenital schistosomiasis transmission on Unguja Island, Zanzibar: characterisation of persistent hot-spots (Publications)
BACKGROUND: Elimination of urogenital schistosomiasis transmission is a priority for the Zanzibar Ministry of Health. Preventative chemotherapy together with additional control interventions have succ
Global, regional, and national incidence, prevalence, and years lived with disability for 310 diseases and injuries, 1990-2015: a systematic analysis... (Publications)
BACKGROUND: Non-fatal outcomes of disease and injury increasingly detract from the ability of the world's population to live in full health, a trend largely attributable to an epidemiological transiti
Re-infection with <em>Fasciola gigantica</em> 6-months post-treatment with triclabendazole in cattle from mobile pastoralist husbandry systems at Lake... (Publications)
At Lake Chad in central Africa, livestock fascioliasis caused by Fasciola gigantica represents a major veterinary health problem, particularly in cattle reared in mobile pastoralist husbandry systems.
Synthesis, DNA binding and antitrypanosomal activity of benzimidazole analogues of DAPI (Publications)
A series of novel benzimidazole diamidines were prepared from the corresponding dicyano analogues either by applying Pinner methodology (5a-c, 10 and 13a) or by making amidoximes intermediates that we
