Joint effect of obesity and TNFA variability on asthma: two international cohort studies (Publications)
Obesity is a risk factor for asthma. Adipose tissue expresses pro-inflammatory molecules including tumour necrosis factor (TNF), and levels of TNF are also related to polymorphisms in the TNF-alpha (T
Defining the next generation of <em>Plasmodium vivax</em> diagnostic tests for control and elimination: target product profiles (Publications)
The global prevalence of malaria has decreased over the past fifteen years, but similar gains have not been realized against Plasmodium vivax because this species is less responsive to conventional ma
Development and evaluation of a bioinformatics approach for designing molecular assays for viral detection (Publications)
BACKGROUND: Viruses belonging to the Flaviviridae and Bunyaviridae families show considerable genetic diversity. However, this diversity is not necessarily taken into account when developing diagnosti
Effectiveness of a 10-day melarsoprol schedule for the treatment of late-stage human African trypanosomiasis: confirmation from a multinational study... (Publications)
BACKGROUND: Treatment of late-stage human African trypanosomiasis (HAT) with melarsoprol can be improved by shortening the regimen. A previous trial demonstrated the safety and efficacy of a 10-day tr
Association between lifetime ambient ozone exposure and pulmonary function in college freshmen: results of a pilot study (Publications)
Human health effects due to chronic exposure to ozone (O3) have not been established due to problems with exposure assignment and the use of measures of lung function which may not reflect the site of
IgE levels, atopy markers and hay fever in relation to age, sex and smoking status in a normal adult Swiss population (Publications)
Within the framework of the SAPALDIA survey (Swiss study on Air Pollution and Lung Diseases in Adults), we studied the influence of sex, age and smoking habits on total serum IgE and allergen-specific
alpha1-Antitrypsin deficiency and lung disease: risk modification by occupational and environmental inhalants (Publications)
Chronic obstructive pulmonary disease (COPD) is a prevalent and preventable disease associated with high morbidity and mortality. Severe and intermediate alpha1-antitrypsin (AAT) deficiency (serum lev
Variation of NO2 and NOx concentrations between and within 36 European study areas: results from the ESCAPE study (Publications)
The ESCAPE study (European Study of Cohorts for Air Pollution Effects) investigates long-term effects of exposure to air pollution on human health in Europe. This paper documents the spatial variation
Risk factors for new-onset cat sensitization among adults: a population-based international cohort study (Publications)
BACKGROUND: Cat exposure during childhood has been shown to increase the risk of developing cat sensitization, while the effect of cat exposure in adulthood has not yet been established. OBJECTIVE: To
