Long-term effects of elemental composition of particulate matter on inflammatory blood markers in European cohorts (Publications)
BACKGROUND: Epidemiological studies have associated long-term exposure to ambient particulate matter with increased mortality from cardiovascular and respiratory disorders. Systemic inflammation is a
The locus <em>C11orf30</em> increases susceptibility to poly-sensitization (Publications)
A number of genetic variants have been associated with allergic sensitization, but whether these are allergen specific or increase susceptibility to poly-sensitization is unknown. Using data from the
Changes in IgE sensitization and total IgE levels over 20 years of follow-up (Publications)
BACKGROUND: Cross-sectional studies have reported a lower prevalence of sensitization in older adults, but few longitudinal studies have examined whether this is an aging or a year-of-birth cohort eff
Spirometer replacement and serial lung function measurements in population studies: results from the SAPALDIA study (Publications)
The Swiss Cohort Study on Air Pollution and Lung and Heart Disease in Adults (SAPALDIA), a population cohort study, used heated-wire spirometers in 1991 and 2002 and then ultrasonic spirometers in 201
Follow-up on genome-wide main effects: do polymorphisms modify the air pollution effect on lung function decline in adults? (Publications)
Improved air quality has been found associated with attenuated age-related decline in lung function. But whether genetic polymorphisms strongly associated with lung function play a modifying role in t
Forschung für Generationen (Publications)
Die ehemalige "Luft- und Lungen-Studie" SAPALDIA ist 20 Jahre alt geworden. Forscherinnen und Forscher aus verschiedensten Disziplinen untersuchen seit Jahren das Zusammenspiel von Umwelt und Gesundhe
Identification of a new locus at 16q12 associated with time-to-asthma onset (Publications)
BACKGROUND: Asthma is a heterogeneous disease in which age of onset plays an important role. OBJECTIVE: We sought to identify the genetic variants associated with time to asthma onset (TAO). METHODS:
Genome-wide association study of lung function decline in adults with and without asthma (Publications)
BACKGROUND: Genome-wide association studies have identified determinants of chronic obstructive pulmonary disease, asthma, and lung function level; however, none have addressed decline in lung functio
