Genome-wide mutational biases fuel transcriptional diversity in the <em>Mycobacterium tuberculosis</em> complex (Publications)
The Mycobacterium tuberculosis complex (MTBC) members display different host-specificities and virulence phenotypes. Here, we have performed a comprehensive RNAseq and methylome analysis of the main c
Safety and tolerance of lymph node biopsies from chronic HIV-1 volunteers in rural Tanzania (Publications)
OBJECTIVE: HIV-1 rapidly establishes a persistent infection that can be contained under life-long antiretroviral therapy (ART) but not cured. One major viral reservoir is the peripheral lymph node (LN
Performance of prediction rules and guidelines in detecting serious bacterial infections among Tanzanian febrile children (Publications)
BACKGROUND: Health-workers in developing countries rely on clinical algorithms, such as the Integrated Management of Childhood Illnesses (IMCI), for the management of patients, including diagnosis of
Host cytoskeleton remodeling throughout the blood stages of <em>Plasmodium falciparum</em> (Publications)
SUMMARYThe asexual intraerythrocytic development of Plasmodium falciparum, causing the most severe form of human malaria, is marked by extensive host cell remodeling. Throughout the processes of invas
Precarity, assemblages and Indonesian elder care (Publications)
The provision (or failure) of care reflects and produces vulnerability in old age. Reliable and appropriate care widely affects the imagination of "good care" of older Indonesians in North Sulawesi. Y
Detection of mutations conferring resistance to linezolid in <em>Enterococcus</em> spp. by fluorescence in situ hybridization (Publications)
A fluorescence in situ hybridization (FISH) assay was established to detect linezolid resistance (conferred by the mutation 2576G> T in the gene coding for the 23 string of the ribosomal RNA) in enter
Evaluation of the Merlin MICRONAUT system for rapid direct susceptibility testing of gram-positive cocci and gram-negative bacilli from positive blood... (Publications)
Bloodstream infections are life-threatening conditions which require the timely initiation of appropriate antimicrobial therapy. We evaluated the automated Merlin MICRONAUT system for rapid direct mic
Rapid transcriptional responses to serum exposure are associated with sensitivity and resistance to antibody-mediated complement killing in invasive... (Publications)
Background: Salmonella Typhimurium ST313 exhibits signatures of adaptation to invasive human infection, including higher resistance to humoral immune responses than gastrointestinal isolates. Full res