<em>Plasmodium falciparum Plasmodium</em> helical interspersed subtelomeric proteins contribute to cytoadherence and anchor <em>P. falciparum</em>... (Publications)
Adherence of Plasmodium falciparum infected erythrocytes to host endothelium is conferred through the parasite-derived virulence factor PfEMP1, the major contributor to malaria severity. PfEMP1 locate
<em>De novo</em> genome assembly shows genome wide similarity between <em>Trypanosoma brucei brucei</em> and <em>Trypanosoma brucei rhodesiense</em> (Publications)
BACKGROUND: Trypanosoma brucei is a eukaryotic pathogen which causes African trypanosomiasis. It is notable for its variant surface glycoprotein (VSG) coat, which undergoes antigenic variation enabled
High functional diversity in <em>Mycobacterium tuberculosis</em> driven by genetic drift and human demography (Publications)
Mycobacterium tuberculosis infects one third of the human world population and kills someone every 15 seconds. For more than a century, scientists and clinicians have been distinguishing between the h
A simple and efficient tool for trapping gravid <em>Anopheles</em> at breeding sites (Publications)
BACKGROUND: No effective tool currently exists for trapping ovipositing malaria vectors. This creates a gap in our ability to investigate the behavior and ecology of gravid Anopheles. FINDINGS: Here w
Reductions in malaria and anaemia case and death burden at hospitals following scale-up of malaria control in Zanzibar, 1999-2008 (Publications)
BACKGROUND: In Zanzibar, the Ministry of Health and partners accelerated malaria control from September 2003 onwards. The impact of the scale-up of insecticide-treated nets (ITN), indoor-residual spra
User-determined end of net life in Senegal: a qualitative assessment of decision-making related to the retirement of expired nets (Publications)
BACKGROUND: Procurement and distribution of long-lasting insecticidal nets (LLINs) in the African region has decreased from 145 million in 2010 to 66 million nets in 2012. As resources for LLIN distri
Deciphering the complex distribution of human immunodeficiency virus type 1 subtypes among different cohorts in Northern Tanzania (Publications)
BACKGROUND: Increased understanding of the genetic diversity of HIV-1 is challenging but important in the development of an effective vaccine. We aimed to describe the distribution of HIV-1 subtypes i
Stealth proteins: in silico identification of a novel protein family rendering bacterial pathogens invisible to host immune defense (Publications)
There are a variety of bacterial defense strategies to survive in a hostile environment. Generation of extracellular polysaccharides has proved to be a simple but effective strategy against the host's