Assessing strategies against <em>gambiense </em>sleeping sickness through mathematical modeling (Publications)
Background: Control of gambiense sleeping sickness relies predominantly on passive and active screening of people, followed by treatment. Methods: Mathematical modeling explores the potential of 3 com
Long-read whole genome sequencing and comparative analysis of six strains of the human pathogen <em>Orientia tsutsugamushi</em> (Publications)
BACKGROUND: Orientia tsutsugamushi is a clinically important but neglected obligate intracellular bacterial pathogen of the Rickettsiaceae family that causes the potentially life-threatening human dis
Rivers as carriers and potential sentinels for <em>Burkholderia pseudomallei </em>in Laos (Publications)
Burkholderia pseudomallei, causative agent of the often fatal disease melioidosis, dwells in tropical soils and has been found in freshwater bodies. To investigate whether rivers are potential habitat
The candidate blood-stage malaria vaccine P27A induces a robust humoral response in a fast track to the field phase I trial in exposed and non exposed... (Publications)
Background: P27A is an unstructured 104mer synthetic peptide from P. falciparum TEX1 blood-stage protein found to be the target of human antibodies inhibiting parasite growth. The present project aime
Safety, immunogenicity, and protective efficacy against controlled human malaria infection of<em> Plasmodium falciparum</em> sporozoites vaccine in... (Publications)
We are using controlled human malaria infection (CHMI) by direct venous inoculation (DVI) of cryopreserved, infectious Plasmodium falciparum (Pf) sporozoites (SPZ) (PfSPZ Challenge) to try to reduce t
Measuring early childhood development at a global scale: evidence from the caregiver-reported early development instruments (Publications)
Despite global interest in supporting and monitoring early childhood development (ECD), few valid and reliable tools exist for capturing ECD at scale across cultural contexts. This study describes the
Reusing treated wastewater: consideration of the safety aspects associated with antibiotic-resistant bacteria and antibiotic resistance genes (Publications)
As more countries engage in water reuse, either intended or de facto, there is an urgent need to more comprehensively evaluate resulting environmental and public health concerns. While antibiotic-resi
Comparison of sensitivity and annoyance to road traffic and community noise between a South African and a Swiss population sample (Publications)
In developing countries, noise annoyance and noise sensitivity are not commonly investigated. The present study aimed to assess the annoyance and sensitivity to noise in 364 adults living in informal
