Precursor-directed diversification of cyclic tetrapeptidic pseudoxylallemycins (Publications)
Cyclic peptides containing non-proteinogenic amino acids often exhibit a broad bioactivity spectrum and many have entered clinical trials with good prospects for drug development. We recently reported
Mathematical modelling of the impact of expanding levels of malaria control interventions on <em>Plasmodium vivax</em> (Publications)
Plasmodium vivax poses unique challenges for malaria control and elimination, notably the potential for relapses to maintain transmission in the face of drug-based treatment and vector control strateg
C-H activation enables a concise total synthesis of quinine and analogues with enhanced antimalarial activity (Publications)
We report a novel approach to the classical natural product quinine that is based on two stereoselective key steps, namely a C-H activation and an aldol reaction, to unite the two heterocyclic moietie
Does the DOSPERT scale predict risk taking behaviour during travel? A study using smartphones (Publications)
Background: Despite the continuing growth of international tourism, very little research has been done on the link between individual risk attitudes and health behaviours during travel. Our study uses
Impact of subtypes and comorbidities on breast cancer relapse and survival in population-based studies (Publications)
OBJECTIVE: To study the impact of subtypes and comorbidities on breast cancer (BC) relapse and survival in the heterogeneous patients of the real world. METHODS: We identified patients diagnosed with
