A research agenda for malaria eradication: health systems and operational research (Publications)
global malaria eradication agenda. In this paper, we (the malERA Consultative Group on Health Systems and Operational Research) focus on the health systems needs of the elimination phase of malaria eradication [...] the pathway to elimination. We examine the difference between the last attempt at eradication of malaria and more recent initiatives, and consider the changing health system challenges as countries make
A high-resolution geospatial surveillance-response system for malaria elimination in Solomon Islands and Vanuatu (Publications)
provinces of Isabel and Temotu, Solomon Islands and Tafea, Vanuatu. Confirmed malaria cases were reported to provincial malaria offices upon diagnosis and updated into the respective SDSS as part of routine [...] surveillance-response system has been developed within a geographic information system (GIS) to support malaria elimination in the Pacific. This paper examines the application of a GIS-based spatial decision support [...] support system (SDSS) to automatically locate and map the...
A research agenda for malaria eradication: monitoring, evaluation, and surveillance (Publications)
how well public health programs operate over time and achieve their goals. As countries approach malaria elimination, these activities will need to shift from measuring reductions in morbidity and mortality [...] there is a clear need to systematically review the information from past elimination efforts for malaria and other infectious diseases
Evaluating the effectiveness of IPTi on malaria using routine health information from sentinel health centres in southern Tanzania (Publications)
of IPTi on malaria, anaemia, and all-cause attendance in children aged 2-11 months presenting to 11 health centres in southern Tanzania is described. METHODS: Clinical diagnosis of malaria was confirmed [...] BACKGROUND: Intermittent preventive treatment of malaria in infants (IPTi) consists of the administration of a treatment dose of sulphadoxine-pyrimethamine (SP) at the time of routine vaccinations. The
Rapid urban malaria appraisal (RUMA) in sub-Saharan Africa (Publications)
BACKGROUND: The rapid urban malaria appraisal (RUMA) methodology aims to provide a cost-effective tool to conduct rapid assessments of the malaria situation in urban sub-Saharan Africa and to improve the [...] site, providing a good overview of the malaria situation. School and health facility-based surveys provided an overview of local endemicity and the overall malaria burden in different city areas. This helped [...] the understanding of urban malaria epidemiology. METHODS: This work was done...
Community-based surveillance of malaria vector larval habitats: a baseline study in urban Dar es Salaam, Tanzania (Publications)
minimal training and supervision in the first weeks of an operational urban malaria control program. METHODS: The Urban Malaria Control Programme of Dar es Salaam recruited and provided preliminary training [...] the population of Africa rapidly urbanizes it may be possible to protect large populations from malaria by controlling aquatic stages of mosquitoes. Here we present a baseline evaluation of the ability [...] CORPs at the start of the Dar es Salaam UMCP were insufficient to enable...
A research agenda for malaria eradication: vector control (Publications)
variety of malaria transmission environments present in the world today. In each setting, improved control for reduction of morbidity is a necessary first step towards the long-range goal of malaria eradication
Generalized seasonal autoregressive integrated moving average models for count data with application to malaria time series with low case numbers (Publications)
The models were applied to monthly malaria case time series in a district in Sri Lanka, where malaria has decreased dramatically in recent years. RESULTS: The malaria series showed long-term changes in [...] INTRODUCTION: With the renewed drive towards malaria elimination, there is a need for improved surveillance tools. While time series analysis is an important tool for surveillance, prediction and for measuring [...] on in the series. CONCLUSIONS: G(S)ARIMA models may be particularly useful...
Efficacy and safety of dihydroartemisinin-piperaquine for treatment of <em>Plasmodium vivax</em> malaria in endemic countries: meta-analysis of... (Publications)
the efficacy of dihydroartemisinin-piperaquine (DHP) in treating uncomplicated Plasmodium vivax malaria in people living in endemic countries. METHODOLOGY AND PRINCIPAL FINDINGS: This is a meta-analysis [...] Findings document that DHP is more efficacious than CQ and AL in treating uncomplicated P. vivax malaria. The better safety profile of DHP and the once-daily dosage improves adherence, and its fixed co [...] the potential to become an alternative antimalarial drug for the treatment...