Efficacy and safety of artemether-lumefantrine in the treatment of acute, uncomplicated <em>Plasmodium falciparum </em>malaria: a pooled analysis (Publications)
and safety of artemether-lumefantrine (AL) for treatment of uncomplicated Plasmodium falciparum malaria. Data from seven studies supported by Novartis (1996-2007), including 647 adults (> 16 years of age
Towards empirical description of malaria seasonality in southern Africa: the example of Zimbabwe (Publications)
BACKGROUND: Quantitative description and mapping of malaria seasonality is important for timely spatial targeting of interventions and for modelling malaria risk. There is a need for seasonality models that [...] use Zimbabwe as an example for developing an empirical map of malaria seasonality. We describe the relationship between seasonality in malaria and environmental covariates for the period 1988--1999, by fitting [...] seasonal trend. We adapt a seasonality concentration index used...
Socially marketed insecticide-treated nets improve malaria and anaemia in pregnancy in southern Tanzania (Publications)
CONCLUSIONS: A modest impact of ITNs on pregnancy malaria and anaemia was shown in our high malaria transmission setting. The development of ITN programmes for malaria control should include pregnant women as a [...] no anaemia, and of high density, low density and no malaria infection by ITN status. Recently treated nets were most effective at preventing malaria and anaemia (prevalence of mild anaemia was 68% compared [...] OBJECTIVES: To study the uptake of socially marketed...
Environmental predictors of the seasonality of malaria transmission in Africa: the challenge (Publications)
A description of malaria seasonality is important for planning and optimizing malaria control in both time and space, but adequate malariologic data are not available for many disease-endemic areas. We [...] between the seasonal dynamics of environmental determinants and malaria pose a great challenge and highlights the need for improved models of malaria seasonality
Effect of malaria on soluble transferrin receptor levels in Tanzanian infants (Publications)
iron deficiency in malaria endemic areas remains unresolved. Three hundred and fourteen infants in a rural area of southern Tanzania living under conditions of intense and perennial malaria transmission were [...] The diagnosis of iron deficiency anemia in malaria endemic areas is complicated by the influence of the infection on the laboratory tests conventionally used to assess iron status. Determination of soluble [...] plasma levels in the assessment of iron deficiency anemia. Independent of...